机构

• 上海药物研究所 [11]
• 昆明植物研究所 [4]
• 化学研究所 [1]
• 大连化学物理研究所 [1]
• 合肥物质科学研究院 [1]
• 昆明动物研究所 [1]
• 更多

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2022 [1]
• 2019 [1]
• 2018 [2]
• 2017 [2]
• 2014 [1]
• 2013 [3]
• 更多

学科主题

• Biochemist... [1]

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Integrated Transcriptomics and Reverse Pharmacophore Mapping-based Network Pharmacology to Explore the Mechanisms of Natural Compounds against Doxorubicin-induced Cardiotoxicity 期刊论文  OAI收割 COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2022, 卷号: 25 作者:  Zhu, Junfeng;  Yi, Xiaojiao;  Ding, Haiying;  Zhong, Like;  Fang, Luo   |  收藏  |  浏览/下载：22/0  |  提交时间：2022/12/22 Doxorubicin-induced cardiotoxicity  natural compounds  mechanism of action  gene expression profile  bioinformatics  network pharmacology   Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文  OAI收割 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316 作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping   |  收藏  |  浏览/下载：57/0  |  提交时间：2019/03/25 IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS   Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699 作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi   |  收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08 Pharmacophore combination  Isoquinoline  PRMT5 inhibitor  Molecular docking  Molecular dynamics simulation   Discovery of FIXa inhibitors by combination of pharmacophore modeling, molecular docking, and 3D-QSAR modeling 期刊论文  OAI收割 JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2018, 卷号: 38, 期号: 3, 页码: 246-255 作者:  Li, Penghua;  Peng, Jiale;  Zhou, Yeheng;  Li, Yaping;  Liu, XingYong   |  收藏  |  浏览/下载：29/0  |  提交时间：2018/12/27 Virtual screening of B-Raf kinase inhibitors: A combination of pharmacophore modelling, molecular docking, 3D-QSAR model and binding free energy calculation studies 期刊论文  OAI收割 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 70, 页码: 186-190 作者:  Zhang, Wen;  Qiu, Kai-Xiong;  Yu, Fang;  Xie, Xiao-Guang;  Zhang, Shu-Qun   |  收藏  |  浏览/下载：24/0  |  提交时间：2017/12/11 B-raf Kinase Inhibitors  Virtual Screening  Pharmacophore  Molecular Docking  3d Qsar  Binding Free Energy Calculation   Exploration of Modern Fixed Dose Combinatorial Medicine Based on Classical Compatibility of Traditional Chinese Medicine 期刊论文  OAI收割 Modernization of Traditional Chinese Medicine and Materia Medica--World Science and Technology, 2017, 卷号: 19, 期号: 11, 页码: 1765-1767 作者:  Huang Chenggang   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Compatibility of traditional Chinese medicine  Chinese medicine compound  pharmacophore basis  research and development of innovative drugs   4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 14, 页码: 3670-3683 作者:  Zhi, Ying;  Gao, Li-Xin;  Jin, Yi;  Tang, Chun-Lan;  Li, Jing-Ya   |  收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B inhibitor  4-Quinolone-3-carboxylic acid  Bidentate ligand  Bioisostere  Insulin receptor signaling   Combinatorial Pharmacophore Modeling of Organic Cation Transporter 2 (OCT2) Inhibitors: Insights into Multiple Inhibitory Mechanisms 期刊论文  OAI收割 MOLECULAR PHARMACEUTICS, 2013, 卷号: 10, 期号: 12, 页码: 4611-4619 作者:  Xu, Yuan;  Liu, Xian;  Li, Shanshan;  Zhou, Nannan;  Gong, Likun   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 organic cation transporter 2 (OCT2)  drug clearance  drug-drug interaction (DDI)  pharmacophore  multiple inhibition mechanism   Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 19, 页码: 5963-5972 作者:  Serrao, Erik;  Xu, Zhong-Liang;  Debnath, Bikash;  Christ, Frauke;  Debyser, Zeger   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 HIV-1  Integrase  LEDGF/p75  5-carbonyl-1H-Imidazole-4-carboxamide  Protein-protein interaction  Antiviral  PDB ID code2B4J   3D-QSAR and pharmacophore model study on aryl diphenolic azoles as estrogen receptor-beta ligands 期刊论文  OAI收割 medicinal chemistry research, 2013, 卷号: 22, 期号: 9, 页码: 4468-4480 作者:  Luo, Hua-Jun;  Zou, Kun;  Huang, Nian-Yu;  Wang, Jun-Zhi;  Deng, Wei-Qiao 收藏  |  浏览/下载：21/0  |  提交时间：2015/11/09 Pharmacophore  3D-QSAR  Estrogen receptor-beta  Prediction