中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共27条,第1-10条 帮助

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Three-fragment fluorescence complementation for imaging of ternary complexes under physiological conditions 期刊论文  iSwitch采集
Analytical chemistry, 2018, 卷号: 90, 期号: 22, 页码: 13299-13305
作者:  
Chen, Minghai;  Li, Wei;  Zhang, Zhi-Ping;  Pan, Jingdi;  Sun, Yuhan
收藏  |  浏览/下载:54/0  |  提交时间:2019/05/08
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1051-1063
作者:  
Zhang, Feng-Hua;  Debnath, Bikash;  Xu, Zhong-Liang;  Yang, Liu-Meng;  Song, Li-Rui
  |  收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文  OAI收割
European Journal of Medicinal Chemistry, 2017, 卷号: 125, 期号: X, 页码: 1051-1063
作者:  
Zhang FH;  Debnath B;  Zheng YT;  Neamati N[*];  Long YQ[*]
收藏  |  浏览/下载:72/0  |  提交时间:2016/11/07
基于界面结构的多靶点HIV-1整合酶抑制剂的发现和结构优化 会议论文  OAI收割
作者:  
张凤华;  许忠良;  李博文;  龙亚秋
  |  收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
2-Aryl-3-carbonylquinolones: Design, Synthesis and Biological Evaluation of Novel HCV NS5B Polymerase Inhibitors 期刊论文  OAI收割
ACTA CHIMICA SINICA, 2014, 卷号: 72, 期号: 8, 页码: 906-913
作者:  
Wang Shenfeng;  Lin Jianping;  He Peilan;  Zuo Jianping;  Long Yaqiu
  |  收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 12, 页码: 3146-3158
作者:  
Li, Bo-Wen;  Zhang, Feng-Hua;  Serrao, Erik;  Chen, Huan;  Sanchez, Tino W.
  |  收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Wikstroelide M potently inhibits HIV replication by targeting reverse transcriptase and integrase nuclear translocation 期刊论文  OAI收割
Chinese Journal of Natural Medicines, 2014, 卷号: 12, 期号: 3, 页码: 186-193
作者:  
Zhang X;  Huang SZ;  Gu WG;  Yang LM;  Chen H
收藏  |  浏览/下载:18/0  |  提交时间:2014/06/03
Discovery of a novel HIV-1 integrase inhibitor from natural compounds through structure based virtual screening and cell imaging 期刊论文  OAI收割
FEBS LETTERS, 2014, 卷号: 588, 期号: 18, 页码: 3461-3468
作者:  
Gu WG;  Zhang X;  Ip DTM;  Yang LM;  Zheng YT
收藏  |  浏览/下载:15/0  |  提交时间:2014/10/10
Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 12, 页码: 3146-3158
作者:  
Li BW;  Zhang FH;  Serrao E;  Chen H;  Sanchez TW
收藏  |  浏览/下载:10/0  |  提交时间:2014/10/15
1,4-Bis(5-(naphthalen-1-yl)thiophen-2-yl)naphthalene, a small molecule, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular Lens epithelium-derived growth factor 期刊论文  OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2014, 卷号: 213, 期号: X, 页码: 21-27
作者:  
Gu WG;  Ip DTM;  Liu SJ;  Chan JH;  Wang Y
收藏  |  浏览/下载:13/0  |  提交时间:2014/10/15