中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 20
作者:
Niu, Pengpeng
;
Tao, Yanxin
;
Lin, Guohao
;
Xu, Huiqi
;
Meng, Qingyuan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma
期刊论文
OAI收割
HAEMATOLOGICA, 2024, 卷号: 109, 期号: 4, 页码: 1206-1219
作者:
Chen, Gege
;
Gao, Xuejie
;
Jia, Xinyan
;
Wang, Yingcong
;
Xu, Li
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4739-4756
作者:
Zhong, Ye
;
Xu, Jing
;
Zhou, Ruochen
;
Tang, Li
;
Ding, Shaoyue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/05/07
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
Hao, Kangwei
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
JE-133 Suppresses LPS-Induced Neuroinflammation Associated with the Regulation of JAK/STAT and Nrf2 Signaling Pathways
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2024, 卷号: 15, 期号: 2, 页码: 258-267
作者:
Tao, Lingxue
;
Yu, Weichen
;
Liu, Ziyi
;
Zhao, Danfeng
;
Lin, Sijin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/02/27
neuroinflammation
microglia
LPS
JAK/STAT
Nrf2
A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization
期刊论文
OAI收割
BIOMATERIALS, 2024, 卷号: 304, 页码: 13
作者:
Luo, Lin-Lin
;
Xu, Jie
;
Wang, Bing-Qiao
;
Chen, Chen
;
Chen, Xi
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/01/26
AAV
Capsid engineering
Phosphosites mutation
Retinal tropism
Neovascularization
Synergistic induction of phytoalexins in Nicotiana attenuata by jasmonate and ethylene signaling mediated by NaWRKY70
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL BOTANY, 2024, 卷号: 75, 期号: 3, 页码: 1063-1080
作者:
Song, Na
;
Wu, Jinsong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/05/09
Alternaria
ethylene
jasmonate
Nicotiana
phytoalexin
scopoletin
scopolin
WRKY
TRANSCRIPTION FACTOR
ALTERNARIA-ALTERNATA
GENE-EXPRESSION
RESISTANCE
ARABIDOPSIS
SCOPOLETIN
ACCUMULATION
PHOSPHORYLATION
BIOSYNTHESIS
PERCEPTION
The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus
期刊论文
OAI收割
VIRULENCE, 2023, 卷号: 14, 期号: 1, 页码: 2171641
作者:
Chen, Feifei
;
Di, Hongxia
;
Wang, Yanhui
;
Peng, Chao
;
Chen, Rongrong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Staphylococcus aureus
Sortase A
protein phosphorylation
virulence