机构

• 上海药物研究所 [6]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2023 [1]
• 2022 [1]
• 2021 [1]
• 2019 [1]
• 2016 [1]
• 2012 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共6条，第1-6条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 115034 作者:  Song, Shukai;  Tang, Haotian;  Ran, Ting;  Fang, Feng;  Tong, Linjiang   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 SyntaLinker  Generative modelling  TBK1 inhibitor  pyrrolo[2  3-d]pyrimidine  Structure-activity relationship   Discovery of Novel Pyrrolo[2,3-d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 2, 页码: 1243-1264 作者:  Liang, Xuewu;  Tang, Shuai;  Liu, Xuyi;  Liu, Yingluo;  Xu, Qifu   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/06/15 Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18 作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng   |  收藏  |  浏览/下载：38/0  |  提交时间：2021/08/17 Axl  Cancer  Inhibitor  Pyrrolo[2,3-d]pyrimidine   Discovery of pyrrolo[3,2-d]pyrimidine-containing compounds as inhibitors of NIK kinase 期刊论文  OAI收割 ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 卷号: 258, 页码: 1 作者:  Zhao, Yu-Jun;  Li, Zhiqiang;  Yan, Ziqing;  Lv, Xilin   |  收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01 Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 17, 页码: 7856-7876 作者:  Golani, Lalit K.;  Wallace-Povirk, Adrianne;  Deis, Siobhan M.;  Wong, Jennifer;  Ke, Jiyuan   |  收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 Identification and synthesis of substituted pyrrolo[2,3-d]pyrimidines as novel firefly luciferase inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: 18, 页码: 5473-5482 作者:  Liu, Yang;  Fang, Jianping;  Cai, Haiyan;  Xiao, Fei;  Ding, Kan   |  收藏  |  浏览/下载：6/0  |  提交时间：2019/01/08 Luciferase  Inhibitor  Pyrrolo[2,3-d]pyrimidine  High-throughput screening  Molecular docking