中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共176条,第1-10条 帮助

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Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:  
Wu, Feifei;  Li, Huiyu;  An, Qi;  Sun, Yaoliang;  Yu, Jinghua
  |  收藏  |  浏览/下载:9/0  |  提交时间:2023/10/17
Discovery of Highly Potent and Selective Thyroid Hormone Receptor βAgonists for the Treatment of Nonalcoholic Steatohepatitis 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3284-3300
作者:  
Hu, Liuyu;  Gu, Yipei;  Liang, Ju;  Ning, Mengmeng;  Yang, Junli
  |  收藏  |  浏览/下载:4/0  |  提交时间:2024/03/27
Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 247, 页码: 115034
作者:  
Song, Shukai
  |  收藏  |  浏览/下载:1/0  |  提交时间:2024/03/27
Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:  
Liang, Xiaofei;  Wang, Chun;  Wang, Beilei;  Liu, Juan;  Qi, Shuang
  |  收藏  |  浏览/下载:39/0  |  提交时间:2022/12/23
Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:  
Song, Jia;  Yang, Rui-rui;  Chang, Jie;  Liu, Ya-dan;  Lu, Cheng-hao
  |  收藏  |  浏览/下载:49/0  |  提交时间:2022/11/11

Design, synthesis, and biological evaluations of substituted pyrazoles as pyrrolomycin analogues against staphylococcal biofilm & nbsp;

期刊论文  OAI收割

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 13
作者:  
Huan, Xiang;  Wang, Yanhui;  Peng, Xiaofeng;  Xie, Shanshan;  He, Qian
  |  收藏  |  浏览/下载:30/0  |  提交时间:2022/08/16

Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold

期刊论文  OAI收割

BIOORGANIC CHEMISTRY, 2022, 卷号: 123, 页码: 12
作者:  
Lu, Haibo;  Lu, Tian;  Zu, Shijia;  Duan, Zhe;  Guang, Yiman
  |  收藏  |  浏览/下载:24/0  |  提交时间:2022/08/16
Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease 期刊论文  OAI收割
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 页码: 16
作者:  
Zeng, Yan;  Nie, Lifei;  Liu, Liu;  Niu, Chao;  Li, Yi
  |  收藏  |  浏览/下载:27/0  |  提交时间:2022/06/15
Discovery of Novel Pyrrolo[2,3-d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 2, 页码: 1243-1264
作者:  
Liang, Xuewu;  Tang, Shuai;  Liu, Xuyi;  Liu, Yingluo;  Xu, Qifu
  |  收藏  |  浏览/下载:38/0  |  提交时间:2022/06/15

Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors (vol 31, 127710, 2021)

期刊论文  OAI收割

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 56, 页码: 1
作者:  
Xiang, Hao-Yue;  Chen, Jian-Yang;  Huan, Xia-Juan;  Chen, Yi;  Gao, Zhao-bing
  |  收藏  |  浏览/下载:22/0  |  提交时间:2022/06/15