中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma
期刊论文
OAI收割
HAEMATOLOGICA, 2024, 卷号: 109, 期号: 4, 页码: 1206-1219
作者:
Chen, Gege
;
Gao, Xuejie
;
Jia, Xinyan
;
Wang, Yingcong
;
Xu, Li
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Regulation of hippo signaling mediated apoptosis by
Rauvolfia tetraphylla
in triple-negative breast cancer
期刊论文
OAI收割
MEDICAL ONCOLOGY, 2024, 卷号: 41, 期号: 5, 页码: 14
作者:
Balavaishnavi, B.
;
Kamaraj, M.
;
Nithya, T. G.
;
Santhosh, P.
;
Gokilalakshmi, S.
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Anti-proliferative effect
Hippo pathway
MDA-MB-231 cells
Apoptosis
Rauvolfia tetraphylla
Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2024, 页码: 12
作者:
Zhang, Huimin
;
Xu, Dounan
;
Huang, Hongchan
;
Jiang, Hao
;
Hu, Linghao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4739-4756
作者:
Zhong, Ye
;
Xu, Jing
;
Zhou, Ruochen
;
Tang, Li
;
Ding, Shaoyue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/05/07
Adenosine-modulating synthetic high-density lipoprotein for chemoimmunotherapy of triple-negative breast cancer
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 367, 页码: 637-648
作者:
Gong, Xiang
;
Zheng, Chao
;
Cai, Ying
;
Zhang, Wen
;
Zhu, Binyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Peptide-drug conjugate
Synthetic high-density lipoprotein
Adenosine
Immunogenic cell death
Immunosuppression
Activatable Janus Nanoparticles for Precise NIR-II Bioimaging and Synergistic Cancer Therapy
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2024, 页码: 16
作者:
Bao, Jiasheng
;
Liu, Ruiqi
;
Yu, Zhouyu
;
Cheng, Zhen
;
Chang, Baisong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
chemodynamic therapy
Janus nanoparticles
NIR-II bioimaging
photothermal therapy
theranostics
Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/25
PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 3, 页码: 419-433
作者:
Tao, Hongru
;
Jin, Chen
;
Zhou, Liyuan
;
Deng, Zhenzhong
;
Li, Xiao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/09
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/04/09