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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海生物化学与细胞... [13]
上海药物研究所 [11]
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期刊论文 [62]
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Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson's disease treatment
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 6, 页码: 1122-1134
作者:
Wang, Qing
;
Yao, Sheng
;
Yang, Ze-xian
;
Zhou, Chen
;
Zhang, Yu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/27
Parkinson's disease
alpha-synuclein aggregation
protein-protein interaction
03A10
MPTP/p model
enema inoculation model
Stimulus-responsive curcumin-based polydopamine nanoparticles for targeting Parkinson's disease by modulating α-synuclein aggregation and reactive oxygen species
期刊论文
OAI收割
Chemical Engineering Journal, 2023, 卷号: 461, 页码: 141606
作者:
Lei, Li
;
Tu, Qiuxia
;
Zhang, Xiaohe
;
Xiang, Song
;
Xiao, Bo
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/03/26
Self-Catalytic Small Interfering RNA Nanocarriers for Synergistic Treatment of Neurodegenerative Diseases
期刊论文
OAI收割
ADVANCED MATERIALS, 2021, 页码: 13
作者:
Ji, Weihong
;
Li, Yan
;
Peng, Huan
;
Zhao, Ruichen
;
Shen, Jie
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/15
brain delivery
nanozymes
neurodegenerative diseases
self-catalysis
siRNA
synergistic treatment
Inhibition of Amyloid Aggregation and Toxicity with Janus Iron Oxide Nanoparticles
期刊论文
OAI收割
CHEMISTRY OF MATERIALS, 2021, 卷号: 33, 期号: 16, 页码: 6484-6500
作者:
Andrikopoulos, Nicholas
;
Song, Zhiyuan
;
Wan, Xulin
;
Douek, Alon M.
;
Javed, Ibrahim
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/12/22
Metabolic Study of Stable Isotope Labeled Indolinone Derivative in Hepatocyte Cell by UPLC/Q TOF MS
期刊论文
OAI收割
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2021, 卷号: 32, 期号: 6, 页码: 1538-1544
作者:
Yang, Jixia
;
Zhang, Gongzheng
;
Wang, Zhaoyang
;
Meng, Jian
;
Wen, Hongliang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/16
indolinone derivatives
alpha-synuclein
[C-3(2), N-15]-isotope labeling, metabolite
UPLC/QTOF
Targeted exosome coating gene-chem nanocomplex as "nanoscavenger" for clearing alpha-synuclein and immune activation of Parkinson's disease
期刊论文
OAI收割
SCIENCE ADVANCES, 2020, 卷号: 6, 期号: 50, 页码: 11
作者:
Liu, Linying
;
Li, Yan
;
Peng, Huan
;
Liu, Ruiyuan
;
Ji, Weihong
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/03/29
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:
Zhang, Yu
;
Wu, Qimei
;
Zhang, Lei
;
Wang, Qing
;
Yang, Zexian
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Caffeic acid
A53T
Parkinson's disease
Autophagy
JNK
Identification of a New alpha-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 6, 页码: 2683-2691
作者:
Xu, Mingming
;
Loa-Kum-Cheung, Wendy
;
Zhang, Haiyan
;
Quinn, Ronald J.
;
Mellick, George D.
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
aggregation
mass spectrometry
screening
inhibitor
Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease
期刊论文
OAI收割
NEUROBIOLOGY OF DISEASE, 2019, 卷号: 124, 页码: 202-217
作者:
Huang, Ya-ru
;
Xie, Xi-xiu
;
Ji, Mei
;
Yu, Xiao-lin
;
Zhu, Jie
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/04/03
Parkinson's disease
alpha-Synuclein
Naturally occurring autoantibodies
A53T mice
WIG