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• 上海药物研究所 [55]
• 昆明植物研究所 [6]
• 武汉病毒研究所 [4]
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• OAI收割 [66]
• iSwitch采集 [5]

内容类型

• 期刊论文 [71]

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• 2018 [3]
• 2016 [3]
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筛选

浏览/检索结果: 共71条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease 期刊论文  OAI收割 JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 页码: 16 作者:  Zeng, Yan;  Nie, Lifei;  Liu, Liu;  Niu, Chao;  Li, Yi   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/06/15 Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16 作者:  Yang, Gui-Xiang;  Sun, Jia-Min;  Zheng, Lu-Lu;  Zhang, Li;  Li, Jie   |  收藏  |  浏览/下载：24/0  |  提交时间：2021/06/11 Vascular dementia  Diosgenin  Antioxidant  Anti-cholinesterase  Multi-target-directed ligands   Anti-foodborne enteritis effect of galantamine potentially via acetylcholine anti-inflammatory pathway in fish 期刊论文  OAI收割 FISH & SHELLFISH IMMUNOLOGY, 2020, 卷号: 97, 期号: 1, 页码: 204-215 作者:     |  收藏  |  浏览/下载：31/0  |  提交时间：2020/04/23 Fish foodbome enteritis  Galantamine  Acetylcholine anti-inflammatory pathway   Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation 期刊论文  OAI收割 JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 5, 页码: 521-530 作者:  Jiang, Cheng-Shi;  Ge, Yong-Xi;  Cheng, Zhi-Qiang;  Song, Jia-Li;  Wang, Yin-Yin   |  收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 AChE inhibitor  Pharmacophore model  Molecular docking  Anti-A aggregation  Neuroprotective activity   Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors 期刊论文  OAI收割 Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288 作者:  Cheng, Zhi-Qiang;  Zhu, Kong-Kai;  Zhang, Juan;  Song, Jia-Li;  Muehlmann, Luis Alexandre   |  收藏  |  浏览/下载：48/0  |  提交时间：2019/01/08 A protective role of autophagy in TDCIPP-induced developmental neurotoxicity in zebrafish larvae 期刊论文  OAI收割 AQUATIC TOXICOLOGY, 2018, 卷号: 199, 期号: 1, 页码: 46-54 作者:  Li, Ruiwen;  Zhang, Ling;  Shi, Qipeng;  Guo, Yongyong;  Zhang, Wei   |  收藏  |  浏览/下载：122/0  |  提交时间：2019/07/03 TDCIPP  Developmental neurotoxicity  Autophagy  LC3 II  Zebrafish larvae   Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345 作者:  Mao, Fei;  Wang, Huan;  Ni, Wei;  Zheng, Xinyu;  Wang, Manjiong   |  收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 Alzheimer's disease  drug repositioning  dual-target inhibitor  AChE inhibition  PDE5 inhibition   neo-Clerodanes from the aerial parts of Salvia leucantha 期刊论文  OAI收割 TETRAHEDRON, 2016, 卷号: 72, 期号: 35, 页码: 5507-5514 作者:  Jiang, Yong-Jun;  Su, Jia;  Shi, Xin;  Wu, Xing-De;  Chen, Xuan-Qin 收藏  |  浏览/下载：40/0  |  提交时间：2016/11/04 neo-Clerodanes  Salvia leucantha  Cytotoxicity  Heat shock protein 90 inhibitor  Acetyl cholinesterase inhibitory activity   Rapid eye movement sleep behavior disorder in patients with probable Alzheimer's disease 期刊论文  OAI收割 Aging Clin Exp Res, 2016, 卷号: 28, 期号: 5, 页码: 951-7 作者:  Wang, P, Wing, Y. K, Xing, J, Liu, Y, Zhou, B, Zhang, Z, Yao, H, Guo, Y, Shang, Y, Zhang, X   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/03/05 Aged,Aged, 80 and over,Alzheimer Disease/*complications,Animals,Cholinesterase Inhibitors/therapeutic use,Electromyography,Female,Humans,Male,Middle Aged,Polysomnography,Probability,REM Sleep BehaviorDisorder/*epidemiology,Sleep/physiology,Sleep, REM/*physiology,Alzheimer's disease,REM sleep behavior disorder,REM sleep without atonia,Video-polysomnography   The discovery of new acetylcholinesterase inhibitors derived from pharmacophore modeling, virtual screening, docking simulation and bioassays 期刊论文  OAI收割 MOLECULAR BIOSYSTEMS, 2016, 卷号: 12, 期号: 12, 页码: 3734-3742 作者:  Zhang, Yunqin;  Zhang, Shuqun;  Xu, Guowei;  Yan, Hui;  Pua, Yinglan 收藏  |  浏览/下载：29/0  |  提交时间：2017/02/14