机构

• 上海药物研究所 [331]
• 海洋研究所 [57]
• 昆明植物研究所 [55]
• 上海生物化学与细胞... [46]
• 昆明动物研究所 [44]
• 西北高原生物研究所 [42]
• 更多

采集方式

• OAI收割 [879]
• iSwitch采集 [50]

内容类型

• 期刊论文 [894]
• 学位论文 [31]
• 会议论文 [4]

发表日期

• 2023 [25]
• 2022 [45]
• 2021 [65]
• 2020 [35]
• 2019 [54]
• 2018 [59]
• 更多

学科主题

• Biochemis... [22]
• Cell Biol... [16]
• Chemistry [16]
• Pharmacol... [13]
• Neuroscie... [12]
• Biochemis... [10]
• 更多

筛选

浏览/检索结果: 共929条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes 期刊论文  OAI收割 DIABETES OBESITY & METABOLISM, 2024, 页码: 9 作者:  Bian, Yi-cong;  Meng, Jian;  Hu, Tao;  Ma, Sheng;  Huang, Chen-rong   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/22 HSK7653  long-acting dipeptidyl peptidase-4 inhibitor  mass balance  metabolism  pharmacokinetics  radiolabelled   Design, Synthesis, and Biological Evaluation of Novel Arylomycins against Multidrug-Resistant Gram-Negative Bacteria 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 25 作者:  Zhang, Yinyong;  Zhang, Dan;  Zhao, Wenhao;  Li, Hongyuan;  Lu, Zhengyu   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/22 Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 222, 页码: 11 作者:  Cheng, Yong -Jun;  Zhuang, Zhen;  Miao, Yu -Ling;  Song, Shan -Shan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 YCH2823  USP7 inhibitor  FT671  BCL6  mTOR inhibitor   New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9 作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Chromone  Thiazolidine-2  4-dione  Protein tyrosine phosphatase 1B  Inhibitors   Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP) 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 2, 页码: 270-279 作者:  Zhou, Chenmao;  Hao, Xinyue;  Chen, Zhengyang;  Zhang, Runze;  Zhou, Qian   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/03/13 Speckle-type POZ protein (SPOP)  SPOP inhibitors  Clear cell renal cell carcinoma (ccRCC)  Structure-activityrelationship (SAR)   Discovery of a PROTAC degrader for METTL3-METTL14 complex 期刊论文  OAI收割 CELL CHEMICAL BIOLOGY, 2024, 卷号: 31, 期号: 1, 页码: 25 作者:  Du, Wenhao;  Huang, Yuting;  Chen, Xiaoai;  Deng, Yue;  Sun, Yaoliang   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/19 Deubiquitylating Enzymes in Cancer and Immunity 期刊论文  OAI收割 ADVANCED SCIENCE, 2023, 页码: 37 作者:  Ren, Jiang;  Yu, Peng;  Liu, Sijia;  Li, Ran;  Niu, Xin   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 cancer  deubiquitylating enzymes (DUBs)  immunity  therapeutic approach   Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9 作者:  Lu, Shiwei;  Zhang, Feng;  Gong, Jiahao;  Huang, Jian;  Zhu, Guanghao   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/08 Cytochrome P450 3A4 (CYP3A4)  Inhibitors  Isoquinoline chalcones  Orally active   Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF) 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12 作者:  Wu, Xinyu;  Wang, Mingchen;  Cao, Yu;  Xu, Ying;  Yang, Ziqun   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/27 O-GlcNAcylation  O-GlcNAc transferase  High-throughput screening  Inhibitor