中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Diterpenoids from Euphorbia peplus possessing cytotoxic and anti-inflammatory activities
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 14
作者:
Li, Ying
;
Yu, Zhi-Pu
;
Li, Yu-Peng
;
Yu, Jin-Hai
;
Yue, Jian-Min
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Euphorbia peplus
Diterpenoids
Cytotoxic activity
Anti-inflammatory activity
NF-kappa B
MAPK
Design and Synthesis of Cyclolipopeptide Mimics of Dysoxylactam A and Evaluation of the Reversing Potencies against P-Glycoprotein-Mediated Multidrug Resistance
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4560-4582
作者:
Yang, Guan-Zhou
;
Wang, Lei
;
Gao, Kun
;
Zhu, Xi
;
Lou, Li-Guang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Targeting JMJD1C to selectively disrupt tumor T
reg
cell fitness enhances antitumor immunity
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2024, 页码: 32
作者:
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/25
Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
Application of ensemble learning for predicting GABA
A
receptor agonists
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2024, 卷号: 169, 页码: 13
作者:
Xiao, Fu
;
Ding, Xiaoyu
;
Shi, Yan
;
Wang, Dingyan
;
Wang, Yitian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/25
GABA(A )receptor
Benzodiazepine
Agonist
Machine learning
Classification
LncRNA pol-lnc78 as a ceRNA regulates antibacterial responses via suppression of pol-miR-n199-3p-mediated SARM down-regulation in Paralichthys olivaceus
期刊论文
OAI收割
ZOOLOGICAL RESEARCH, 2024, 卷号: 45, 期号: 1, 页码: 25-35
作者:
Ning, Xian-Hui
;
Han, Bing
;
Peng, Ye
;
Yin, Shao-Wu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/07
LncRNA
SARM
miRNA
ceRNA
Antibacterial response
Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 17
作者:
Pu, Congying
;
Li, Yize
;
Fu, Yixian
;
Yan, Yiyang
;
Tao, Siyao
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/02/27
AIM2 inflammasome
chemotherapy
gut microbiome
ileal epithelial cells
immune checkpoint blockade
lactobacillus
segmented filamentous bacterium
Co-delivering irinotecan and imiquimod by pH-responsive micelle amplifies anti-tumor immunity against colorectal cancer
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 卷号: 648, 页码: 14
作者:
Yan, Wenlu
;
Li, Yu
;
Zou, Yiting
;
Zhu, Runqi
;
Wu, Ting
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2024/01/16
Colorectal cancer
Irinotecan
Imiquimod
Micelle
Immune response
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study
期刊论文
OAI收割
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
作者:
Zhao, Tian-Tian
;
Hu, Hao-Jie
;
Gao, Li-Xin
;
Zhou, Yu-Bo
;
Zhu, Yun-Long
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Protein tyrosine phosphatases inhibitors
PTP1B inhibitors
Mechanism study
Molecular dynamics
Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 50, 期号: 12, 页码: 2856-2868
作者:
Wang, Yun-Qi
;
Guan, Zi-Yue
;
Gao, Zhao-Bing
;
Zheng, Yue-Ming
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/09
TRPM7
ion channel
physiological function
disease
small molecule modulators