中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [37]
大连化学物理研究所 [14]
合肥物质科学研究院 [5]
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期刊论文 [62]
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Co-delivering irinotecan and imiquimod by pH-responsive micelle amplifies anti-tumor immunity against colorectal cancer
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 卷号: 648, 页码: 14
作者:
Yan, Wenlu
;
Li, Yu
;
Zou, Yiting
;
Zhu, Runqi
;
Wu, Ting
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/16
Colorectal cancer
Irinotecan
Imiquimod
Micelle
Immune response
Combination of irinotecan silicasome nanoparticles with radiation therapy sensitizes immunotherapy by modulating the activation of the cGAS/STING pathway for colorectal cancer
期刊论文
OAI收割
MATERIALS TODAY BIO, 2023, 卷号: 23, 页码: 16
作者:
Wang, Lu
;
Zhang, Tianyu
;
Zheng, Yile
;
Li, Yuting
;
Tang, Xiyuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
;
Sun, Mengru
;
Zou, Kun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity
Pulmonary Large Cell Neuroendocrine Carcinoma
期刊论文
OAI收割
PATHOLOGY & ONCOLOGY RESEARCH, 2022, 卷号: 28
作者:
Yang, Lan
;
Fan, Ying
;
Lu, Hongyang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/23
treatment
diagnosis
LCNEC
imaging examination
pathologic features
prognosis
Efficacy and safety of radiotherapy combined with raltitrexed and irinotecan for treating unresectable recurrent colorectal cancer: a single-arm phase II trial
期刊论文
OAI收割
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2022
作者:
Li, Xinghui
;
Shen, Jinwen
;
Xia, Fan
;
Zhu, Ji
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2022/12/23
Colorectal cancer
local recurrence
intensity-modulated radiotherapy
irinotecan
raltitrexed
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:
Huang, Ying
;
Wang, Lei
;
Cheng, Zhiyang
;
Yang, Biyu
;
Yu, Jiahui
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/12/01
Antitumour
Chemotherapy
SN38
Drug delivery systems
Albumin
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
OAI收割
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY
Anti-PD-Ll mediating tumor-targeted codelivery of liposomal irinotecan/JQl for chemo-immunotherapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 9, 页码: 1516
作者:
He Zhidi
;
Zhang Meng
;
Wang Yonghui
;
He Yang
;
Wang Hairui
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/05/22
tumor-targeted delivery
immunogenic cell death
PD-1/PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint
Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
He, Zhi-di
;
Zhang, Meng
;
Wang, Yong-hui
;
He, Yang
;
Wang, Hai-rui
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/05/24
tumor-targeted delivery
immunogenic cell death
PD-1
PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint