中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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A validated LC-MS/MS method for the quantitation of daratumumab in rat serum using rapid tryptic digestion without IgG purification and reduction
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8
作者:
Li, Weiqiang
;
Huang, Wensi
;
Yu, Xiong
;
Chen, Chong
;
Yuan, Yali
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Daratumumab
LC-MS/MS
Surrogate peptide
Pharmacokinetics
Spatiotemporal Quantification of HER2-targeting Antibody-Drug Conjugate Bystander Activity and Enhancement of Solid Tumor Penetration
期刊论文
OAI收割
CLINICAL CANCER RESEARCH, 2024, 卷号: 30, 期号: 5, 页码: 984-997
作者:
Wei, Qing
;
Yang, Teng
;
Zhu, Jiayu
;
Zhang, Ziwen
;
Yang, Le
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Eliminating drug target interference with specific antibody or its F(ab′)
2
fragment in the bridging immunogenicity assay
期刊论文
OAI收割
BIOANALYSIS, 2024, 页码: 14
作者:
Deng, Xiaojie
;
Hou, Yingying
;
Yuan, Wenyi
;
Yang, Hongzhou
;
Guo, Ruowen
  |  
收藏
  |  
浏览/下载:280/0
  |  
提交时间:2024/04/09
anti-drug antibody
IgE
immunogenicity
mitigation
target interference
A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11
作者:
Huang, Wen-si
;
Li, Wei-qiang
;
Yu, Xiong
;
Xue, Ming-zhen
;
Yuan, Ya-li
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/04/09
Anti -gastric cancer monoclonal antibody
Ramucirumab
LC -MS/MS
Method validation
Surrogate peptide
SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Li, Wen-jing
;
Xie, Cheng-ying
;
Zhu, Xi
;
Tang, Jiao
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/02/19
SIBP-03
HER3
HER3-targeted therapy
neuregulin 1
EGFR
HER2
Development, methodological evaluation and application of a cell-based TRF assay for analysis of ADCC activity
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 7
作者:
Zhu, Xiao
;
Gong, Likun
;
Qin, Qiuping
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Antibody-dependent cell-mediated cytotoxicity
Time-resolved fluorescence
Monoclonal antibody
Antibody-Drug Conjugate
Eu
NK-92 cells
A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 11
作者:
Zhou, Ainan
;
Yu, Jinghua
;
Wu, Yali
;
Xue, Hao
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Monoclonal antibody
Bevacizumab
LC-MS
MS
Surrogate peptide
Pharmacokinetics
Serum
Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)
Conjugation site characterization of antibody-drug conjugates using electron-transfer/higher-energy collision dissociation (EThcD)
期刊论文
OAI收割
ANALYTICA CHIMICA ACTA, 2023, 卷号: 1251, 页码: 7
作者:
Song, Yuanli
;
Gao, Jing
;
Meng, Qian
;
Tang, Feng
;
Wang, Yuqiu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
Antibody -drug conjugates
EThcD
Conjugation site
Peptide mapping
Quality control
Enhanced antibody-defucosylation capability of a-L-fucosidase by proximity-based protein fusion
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 645, 页码: 40-46
作者:
Fan, Shuquan
;
Li, Wanzhen
;
Zhang, Kuixing
;
Zou, Xiangman
;
Shi, Wei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/04/10