中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
植物研究所 [5]
上海生物化学与细胞生... [3]
上海神经科学研究所 [2]
大连化学物理研究所 [1]
水生生物研究所 [1]
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OAI收割 [23]
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期刊论文 [22]
会议论文 [1]
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2024 [1]
2023 [1]
2021 [1]
2020 [3]
2019 [2]
2018 [4]
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Plant Scie... [5]
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Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 17
作者:
Yu, Qian
;
Wang, Zheng
;
Tu, Yutong
;
Cao, Yu
;
Zhu, Huajian
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
20S proteasome
Proteasome activation
IDPs
Undruggable
Protein homeostasis
Structure-based discovery of potent USP28 inhibitors derived from Vismodegib
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Zhou, Di
;
Xu, Zhuo
;
Huang, Yaodong
;
Wang, Hui
;
Zhu, Xiaoli
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
USP28
Structure-based
Vismodegib derivatives
Structure-activity relationships
c-Myc
Ubiquitin-independent proteasome system is required for degradation of Arabidopsis COPPER TRANSPORTER 2
期刊论文
OAI收割
PLANT SCIENCE, 2021, 卷号: 304
作者:
Li, Jinjin
;
Wang, Weiwei
;
Yuan, Jinhong
;
Xu, Jinyu
;
He, Lifei
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/02/24
COPT2
Arabidopsis
Vacuolar degradation
Proteasome
Ubiquitin
Vesicle trafficking
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Chen, Xiang-ling
;
Liu, Peng
;
Zhu, Wei-liang
;
Lou, Li-guang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
DCZ5248
Hsp90
autophagy
lysosomal function
antitumor activity
colon cancer
Arabidopsis COPPER TRANSPORTER 1 undergoes degradation in a proteasome-dependent manner
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL BOTANY, 2020, 卷号: 71, 期号: 19, 页码: 6174-6186
作者:
Li, Jinjin
;
Yuan, Jinhong
;
Wang, Hui
;
Zhang, Hui
;
Zhang, Haiyan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/06
Arabidopsis
copper transporter
degradation
proteasome
ubiquitination
vesicle trafficking
Arabidopsis COPPER TRANSPORTER 1 undergoes degradation in a proteasome-dependent manner
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL BOTANY, 2020, 卷号: 71, 期号: 19, 页码: 6174-6186
作者:
Li, Jinjin
;
Yuan, Jinhong
;
Wang, Hui
;
Zhang, Hui
;
Zhang, Haiyan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2022/03/01
Arabidopsis
copper transporter
degradation
proteasome
ubiquitination
vesicle trafficking
Inhibition of HSP90 beta Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System
期刊论文
OAI收割
THERANOSTICS, 2019, 卷号: 9, 期号: 20, 页码: 5769-5783
作者:
Zheng, Zu-Guo
;
Zhang, Xin
;
Liu, Xiao-Xiao
;
Jin, Xiu-Xiu
;
Dai, Lunzhi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
HSP90 beta
lipid metabolism
corylin
SREBPs
proteasomal degradation
Inhibition of HSP90 beta Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System
期刊论文
OAI收割
THERANOSTICS, 2019, 卷号: 9, 期号: 20, 页码: 5769-5783
作者:
Zheng, Zu-Guo
;
Zhang, Xin
;
Liu, Xiao-Xiao
;
Cheng, Hui-Min
;
Jing, Dan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/09
HSP90 beta
lipid metabolism
corylin
SREBPs
proteasomal degradation
Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:
Liu, Bin
;
Jiang, Shangwen
;
Li, Min
;
Xiong, Xuelian
;
Zhu, Mingrui
  |  
收藏
  |  
浏览/下载:109/0
  |  
提交时间:2019/01/08
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
作者:
Zhu, Xiaoliang
;
Yuan, Chunmao
;
Tian, Chenyang
;
Li, Chen
;
Nie, Fen
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2018/05/08
Inhibitor
Protein Synthesis
Small Molecule
T-cell Factor (Tcf)
Wnt Signaling