中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Fluorescence-Coupled Ubiquitination Assay as a High-Throughput Screening Strategy for Novel Cereblon Degraders
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 10111-10127
作者:
Deng, Yanan
;
Yang, Shiling
;
Xu, Hesong
;
Ding, Xiyao
;
Xu, Ying
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/06/23
O
-Cyanobenzaldehydes Irreversibly Modify Both Buried and Exposed Lysine Residues in Live Cells
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 14, 页码: 11955-11963
作者:
Ling, Huan
;
Li, Lin
;
Duan, Liping
;
Huang, Weixue
;
Zheng, Jiangnan
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
J-TEXT achievements in turbulence and transport in support of future device/reactor
期刊论文
OAI收割
PLASMA SCIENCE & TECHNOLOGY, 2024, 卷号: 26
作者:
Chen, Zhipeng
;
Huang, Zhangsheng
;
Jiang, Min
;
Long, Ting
;
Wang, Lu
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/11/20
J-TEXT tokamak
turbulence
transport
flow
Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 148, 页码: 15
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Wu, Jianbo
;
Zhang, Ying
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/09/26
Cyclin-dependent kinase 7
Small molecular inhibitor
Triple negative breast cancer
Thieno[3,2-d]pyrimidine derivative
A Novel Drug Candidate for Sepsis Targeting Heparanase by Inhibiting Cytokine Storm
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 15
作者:
Wang, Danyang
;
Wang, Kaixuan
;
Liu, Qiutong
;
Liu, Mingyang
;
Zhang, Guoqiang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/07/12
cytokine storm
glycocalyx
heparanase
sepsis
Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 20
作者:
Niu, Pengpeng
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/05/22
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
Effect of laparoscopy-assisted vs open surgery on 3-year disease-free survival in patients with low rectal cancer: The LASRE randomized clinical trial.
期刊论文
OAI收割
JOURNAL OF CLINICAL ONCOLOGY, 2024, 卷号: 42
作者:
Chi, Pan
;
Su, Xiangqian
;
Xu, Jianmin
;
Qiu, Huizhong
;
Wang, Ziqiang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/11/20
613-4678-4781-4031
283-237-255-1133
261-492-3532-2370-7650-2700
261-492-3532-2370-7650-2454
613-616-498
261-492-341-2431
7
4
3
3
2
2
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2024/04/09
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer