中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [62]
青海盐湖研究所 [49]
大连化学物理研究所 [28]
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期刊论文 [249]
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Structural optimization and discovery of high effective isopropanolamine-based TPS1 inhibitors as promising broad-spectrum fungicide candidates
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 290, 页码: 17
作者:
Jiang, Zhiyang
;
Wang, Na
;
Chen, Jinxiu
;
Xu, Huan
;
Zhu, Wenya
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/05/27
Trehalose-6-phosphate synthase
Structural optimization
Isopropanolamine compounds
Inhibitors
Fungicide candidates
Pentavalent pnictogen bonds involving triarylpnictogen catecholates as strong Lewis acids: Crystallographic survey and theoretical analysis
期刊论文
OAI收割
COMPUTATIONAL AND THEORETICAL CHEMISTRY, 2025, 卷号: 1248, 页码: 9
作者:
Liu, Ruotong
;
Han, Zijian
;
Lu, Yunxiang
;
Xu, Zhijian
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/27
Pentavalent PnBs
Triarylpnictogen(V) catecholates
CSD search
Theoretical
Development of RelB-targeting small-molecule inhibitors of non-canonical NF-kB signaling with antitumor efficacy
期刊论文
OAI收割
MOLECULAR THERAPY, 2025, 卷号: 33, 期号: 4, 页码: 1519-1534
作者:
Li, Cuifeng
;
Wei, Shuqi
;
Sun, Donglin
;
Yang, Zhuo
;
Wang, Qi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
B(MIDA)-directed site-selective intermolecular halofluoroalkylation of alkenes: synthesis of diversely functionalized building blocks
期刊论文
OAI收割
CHEMICAL SCIENCE, 2025, 页码: 8
作者:
Wu, Hengbo
;
Luo, Ruitong
;
Peng, Jingjing
;
Han, Zijian
;
Zhang, Renjie
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/04/01
Identification of the VP37 pocket of monkeypox virus as a promising target for pan-orthopoxvirus inhibitors through virtual screening and antiviral assays
期刊论文
OAI收割
EMERGING MICROBES & INFECTIONS, 2024, 卷号: 13, 期号: 1, 页码: 4
作者:
Huo, Shuting
;
Wu, Leyun
;
Huang, Baoying
;
Liu, Nan
;
Sun, Jiewei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/08/22
Cation-anion chalcogen bonds in ion pairs: A combined crystallographic survey and computational investigation
期刊论文
OAI收割
COMPUTATIONAL AND THEORETICAL CHEMISTRY, 2024, 卷号: 1242, 页码: 11
作者:
Liu, Hui
;
Han, Zijian
;
Lu, Yunxiang
;
Xu, Zhijian
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/12/25
Cation-anion ChBs
Ion-pairing complexes
CSD survey
Computational
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248
作者:
Wang, Yingying
;
Zhang, Youping
;
Luo, Hao
;
Wei, Wei
;
Liu, Wanting
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/04/01
Ubiquitin-specific protease 2
KRAS
Gambogic acid
Multiple myeloma
Degradation
Ubiquitination
Allosteric pocket
Deubiquitination
Slow Metabolism-Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone-Induced Obesity-Specific Liver Injury
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 14
作者:
Li, Guanting
;
Hu, Yourong
;
Zhao, Han
;
Peng, Ziyu
;
Shang, Xin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/01/06
benzbromarone
drug-induced liver injury
drug metabolism
obesity
PPAR gamma
Regulation of interstitial fluid flow in adventitia along vasculature by heartbeat and respiration
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 4, 页码: 22
作者:
Li, Hongyi
;
Li, Bei
;
Luo, Wenqi
;
Qi, Xi
;
Hao, You
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/06
Rational design and discovery of novel oxalate-like derivatives as aphid-repellent candidates based on odorant-binding protein 3
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1301, 页码: 11
作者:
Zhu, Ziwei
;
Li, Jianing
;
Liu, Chong
;
Li, Huilin
;
Lu, Xingxing
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/04/09
Odorant-binding protein
Oxalate-like derivatives
Rational design
Repellent activity
Behavioural control agents