中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [213]
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Brain Resident Ly6Chi Monocytes Are Necessary for Maintaining Adult Hippocampal Neurogenesis
期刊论文
OAI收割
AGING AND DISEASE, 2025, 页码: 20
作者:
Huang, Yiran
;
Gao, Nan
;
Liu, Boren
;
Luo, Weili
;
Chen, Jianfei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/01/14
Monocytes
Stress
Bone marrow homing
Adult hippocampal neurogenesis
Reversing tumor fibrosis for potentiating chemo-immunotherapy via lactic acid exhaustion by codelivery of bicarbonate and JQ1
期刊论文
OAI收割
NANO TODAY, 2025, 卷号: 61, 页码: 16
作者:
Peng, Taoxing
;
He, Yihao
;
Shao, Xinyue
;
Liu, Han
;
Yang, Lu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/01
sodium bicarbonate
Nano-adjuvant
Lactic acid exhaustion
Tumor fibrosis reversal
Chemo-immunotherapy
A holistic strategy for the in-depth discrimination and authentication of 16 citrus herbs and associated commercial products based on machine learning techniques and non-targeted metabolomics
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2025, 卷号: 1745, 页码: 12
作者:
Huang, Yu-shi
;
An, Ya-ling
;
Zheng, Yue-yuan
;
Zhao, Wen-jie
;
Song, Chun-qian
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
Citrus herbs
Discrimination
LC-MS
Machine learning
Differential markers
Pentacyclic triterpenoids with cytotoxic activity from the stems of
Syzygium
jambos
(L.) Alston
期刊论文
OAI收割
FITOTERAPIA, 2025, 卷号: 181, 页码: 7
作者:
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Syzygium jambos
Pentacyclic triterpenoids
Oleanane
Ursane
Cytotoxicity
Raddeanin A suppresses intracellular
5
Methylcytosine DNA modification engaged the metastasis of hepatocellular carcinoma
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 338, 页码: 11
作者:
Liu, Xin
;
Xie, Xiaoyan
;
Wang, Kangyu
;
Liu, Xiaokang
;
Gong, Jiyu
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/01/14
Raddeanin a (RA)
Hepatocellular carcinoma (HCC)
DNA methyltransferase (DNMT)
Tumorigenesis and metastasis
Pharmacodynamic effect
Ligand-binding assays validated for quantitative bioanalysis of a novel antibody-drug conjugate in monkey serum and related application in a nonclinical study
期刊论文
OAI收割
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2025, 卷号: 131, 页码: 11
作者:
Hou, Yingying
;
Miao, Jie
;
Sun, Yajun
;
Shi, Lili
;
Lu, Ouyang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
ADC
LBA
Validation
GLP
PK
In-situ trichosanthin-IL2/pectin dynamic hydrogel activates dendritic cells and reverses T cell exhaustion for post-operative cancer therapy
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2025, 卷号: 505, 页码: 12
作者:
Gu, Zeyun
;
Chen, Guihua
;
Gao, Nan
;
Yao, Shuo
;
Zhang, Xiaoru
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Trichosanthin
IL2
Hydrogel
Postoperative administration
Cancer immunotherapy
Dendritic cells
Hemodynamic and Pharmacokinetic Interactions of TPN171 with Alcohol in Healthy Male Subjects
期刊论文
OAI收割
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2025, 卷号: 18, 期号: 2, 页码: 8
作者:
Cheng, Jie
;
Qian, Hongjie
;
Wang, Yu
;
Liang, Liyu
;
Xu, Wenjing
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/01
alcohol
healthy subjects
hemodynamics
PDE5 inhibitor
pharmacokinetics
TPN171
Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma
期刊论文
OAI收割
CELL DISCOVERY, 2025, 卷号: 11, 期号: 1, 页码: 24
作者:
Cheng, Yifei
;
Chen, Xiaofang
;
Feng, Li
;
Yang, Zhicheng
;
Xiao, Liyun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect