机构

• 上海药物研究所 [19]
• 重庆绿色智能技术研究... [2]
• 上海营养与健康研究所 [2]
• 昆明植物研究所 [1]
• 过程工程研究所 [1]
• 中国科学院大学 [1]
• 更多

采集方式

• OAI收割 [26]
• iSwitch采集 [1]

内容类型

• 期刊论文 [26]
• 专利 [1]

发表日期

• 2024 [2]
• 2023 [4]
• 2022 [7]
• 2021 [2]
• 2019 [2]
• 2018 [1]
• 更多

学科主题

• Biotechnol... [1]
• Endocrinol... [1]

筛选

浏览/检索结果: 共27条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 17, 页码: 15220-15245 作者:  Saidahmatov, Abdusaid;  Li, Jianan;  Xu, Shihao;  Hu, Xiaobei;  Gao, Xiangqian   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/10/21 Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759 作者:  Liu, Zhi;  Jiang, Kailong;  Liu, Yan;  Li, Junfei;  Huang, Siqi   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/09/26 Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/02/19 Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Li, Xuemei;  Wang, Peipei;  Wang, Chang;  Jin, Tingting;  Xu, Ran   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 A comprehensive analysis of the Bencao (herbal) small RNA Atlas reveals novel RNA therapeutics for treating human diseases 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 19 作者:  Cao, Yinghao;  Lin, Yexuan;  Sun, Na;  Du, Xinyi;  Dong, Yixin   |  收藏  |  浏览/下载：50/0  |  提交时间：2023/10/17 small RNA  herbal decoction  cross-kingdom regulation  traditional Chinese medicine  RNA oligonucleotide drug  RNA therapeutics  Bencao small RNA Atlas   Targeting C/EBP alpha overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18 作者:  Wang, Hanlin;  Luo, Guanghao;  Hu, Xiaobei;  Xu, Gaoya;  Wang, Tao   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia 期刊论文  OAI收割 LEUKEMIA, 2022, 页码: 11 作者:  Jiang, Kailong;  Li, Xuemei;  Wang, Chang;  Hu, Xiaobei;  Wang, Peipei   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/04/10 Design, synthesis, and biological evaluation of Wee1 kinase degraders 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243, 页码: 21 作者:  Zhu, Shulei;  Liu, Jieyu;  Xiao, Donghuai;  Wang, Peipei;  Ma, Jingkun   |  收藏  |  浏览/下载：59/0  |  提交时间：2022/11/11 CRBN  Wee1  PROTAC  Degradation   Malto-oligosaccharides as critical functional ingredient: a review of their properties, preparation, and versatile applications 期刊论文  OAI收割 CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2022, 页码: 13 作者:  Ji, Hangyan;  Liu, Jialin;  McClements, David Julian;  Bai, Yuxiang;  Li, Zhitao   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/12/13 Malto-oligosaccharides  functional ingredient  physicochemical properties  enzymatic preparation  versatile applications   Superhydrophobic Materials: Versatility and Translational Applications 期刊论文  OAI收割 ADVANCED MATERIALS INTERFACES, 2022, 页码: 29 作者:  Yong, Haiyang;  Li, Zhili;  Huang, Xiaobei;  Wang, Kaixuan;  Zhou, Ya-Nan   |  收藏  |  浏览/下载：53/0  |  提交时间：2022/10/14 fabrication technology  practical application  superhydrophobic material  versatility