中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [31]
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烟台海岸带研究所 [18]
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期刊论文 [129]
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Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
Zeng, Yanping
;
Xiao, Jian
;
Shi, Li
;
Li, Yangsha
;
Xu, Yuanxin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Exploratory research on the effective chemical basis of tanreqing injection for treating acute lung injury: In vivo, in vitro and in silico
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 337, 页码: 11
作者:
Tang, Bixi
;
Xie, Like
;
Wang, Yangyang
;
Shi, Yulong
;
Kan, Weijuan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/11/26
Lung first-pass effect
Tanreqing injection
Pharmacokinetics
Sepsis-associated acute lung injury
Acute respiratory distress syndrome
Fibroblast activation protein peptide-targeted NIR-I/II fluorescence imaging for stable and functional detection of hepatocellular carcinoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2025, 页码: 14
作者:
Lin, En
;
Song, Miaomiao
;
Wang, Bo
;
Shi, Xiaojing
;
Zhao, Jiali
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Hepatocellular carcinoma
Cancer-associated fibroblasts
Fibroblast activation protein
Near-infrared fluorescence
Peptide-targeted fluorescence imaging
Effect of ocean dynamic processes on the temporal-spatial pattern of persistent organic pollutants (PCB-153 and BDE-47) in the shelf seas
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2024, 卷号: 480, 页码: 11
作者:
Wang, Aobo
;
Guo, Xinyu
;
Ding, Xiaokun
;
Shi, Jie
;
Tang, Jianhui
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/01/10
Coupled model
Bottom cold water mass
Spatial distribution
Persistent organic pollutants
Prediction function
Highly oxygenated steroids with immunosuppressive activity from
Solanum undatum
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 页码: 7
作者:
Chen, Shu-Shuai
;
Zheng, Cheng-Yu
;
Yang, Guan-Zhou
;
Zhou, Jun-Su
;
He, Shi-Jun
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/12/11
Synthesis and Biological Activity of Tetracyclic Dispiro Core Derivatives of Natural Products Dispirocochlearoids A-C
期刊论文
OAI收割
ORGANIC LETTERS, 2024, 卷号: 26, 期号: 45, 页码: 9654-9658
作者:
Pei, Junping
;
Wang, Ying
;
Shi, Shengjie
;
Chen, Linhai
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/11
Discovery of Potent and Selective G9a Degraders for the Treatment of Pancreatic Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 13271-13285
作者:
Shi, Yunkai
;
Shen, Qianqian
;
Long, Ruikai
;
Mao, Yiwen
;
Tong, Shuaihang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/09/26
Targeting CCL2-CCR2 signaling pathway alleviates macrophage dysfunction in COPD via PI3K-AKT axis
期刊论文
OAI收割
CELL COMMUNICATION AND SIGNALING, 2024, 卷号: 22, 期号: 1, 页码: 19
作者:
Dong, Yue
;
Dong, Ying
;
Zhu, Chengyue
;
Yang, Lan
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/08/22
Chronic obstructive pulmonary disease
C-C motif chemokine ligand 2
C-C chemokine receptor type 2
Bronchial epithelial cells
Macrophage
Quinazoline-2,4
(1 H
,
3 H
)-dione Scaffold for development of a novel PARP-targeting PET probe for tumor imaging
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2024, 页码: 14
作者:
He, Chunfeng
;
Shi, Hui
;
Tan, Boyu
;
Jiang, Zhaoning
;
Cao, Rui
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/22
PARP
Oncology
Quinazoline-2,4(1H,3H)-dione
PET/CT
Nature Products Chlorophyll Derivatives for NIR-II Fluorescence Bioimaging and Plant-Imaging
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2024, 页码: 10
作者:
Chen, Kaixin
;
Shi, Hui
;
Li, Lei
;
Yang, Mao
;
Qian, Kun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/08/22
NIR-II
Chlorophyll
Imaging
Nature product