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筛选

浏览/检索结果: 共174条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22 作者:  Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/12/11 SARS-CoV-2  3CL pro inhibitors  Peptidomimetics  Spiropyrrolidine derivatives   F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13 作者:  Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/02/28 Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248 作者:  Wang, Yingying;  Zhang, Youping;  Luo, Hao;  Wei, Wei;  Liu, Wanting   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/04/01 Ubiquitin-specific protease 2  KRAS  Gambogic acid  Multiple myeloma  Degradation  Ubiquitination  Allosteric pocket  Deubiquitination   TRIP13-a potential drug target in cancer pharmacotherapy 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 151, 页码: 11 作者:  Bunu, Samuel Jacob;  Cai, Haiyan;  Wu, Leyun;  Zhang, Hui;  Zhou, Zhaoyin   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/09/26 AAA plus ATPase  TRIP13  Cancer  Drug target  Small-molecule inhibitors   Development of ketalized unsaturated saccharides as multifunctional cysteine-targeting covalent warheads 期刊论文  OAI收割 COMMUNICATIONS CHEMISTRY, 2024, 卷号: 7, 期号: 1, 页码: 10 作者:  Dong, Sanfeng;  Huang, Hui;  Li, Jintian;  Li, Xiaomei;  Bunu, Samuel Jacob   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/10/21 Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16 作者:  Zheng, Jiefang;  Zhou, Liping;  Gong, Xudong;  Yang, Feipu;  Cheng, Jiaxin   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/08/22 Triple reuptake inhibitors  5-HT 1A R agonists  Antidepressants  Multimodal serotonergic compounds   Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16 作者:  Li, Xiaomei;  Zhang, Hui;  Dong, Sanfeng;  Gao, Xuejie;  Sun, Haiguo   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/09/26 Multiple myeloma  1-amido-2-one-4-thio-deoxypyranose  TRIP13 inhibitor  In vivo activity   Development of an FAP-Targeted PET Probe Based on a Novel Quinolinium Molecular Scaffold 期刊论文  OAI收割 BIOCONJUGATE CHEMISTRY, 2024, 页码: 9 作者:  Li, Lei;  Cao, Rui;  Chen, Kaixin;  Qu, Chunrong;  Qian, Kun   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/08/22 Switchable Regioselective C-H Activation/Annulation of Acrylamides with Alkynes for the Synthesis of 2-Pyridones 期刊论文  OAI收割 CHEMSUSCHEM, 2024, 页码: 9 作者:  Chen, Chao;  Chen, Yanni;  Han, Zijian;  Huang, Yujie;  Wang, Yujiao   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/06/27 C-H activation  [4+2] annulation  switchable regioselectivity  2-pyridones  redox-neutral   Impact of Halogen Bonds on Protein-Peptide Binding and Protein Structural Stability Revealed by Computational Approaches 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 11 作者:  Li, Jintian;  Zhou, Liping;  Han, Zijian;  Wu, Leyun;  Zhang, Jianfang   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/05/07