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浏览/检索结果: 共195条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22 作者:  Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/12/11 SARS-CoV-2  3CL pro inhibitors  Peptidomimetics  Spiropyrrolidine derivatives   F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13 作者:  Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/02/28 Direct Reductive N-alkylation of Amines with Carboxylic Esters 期刊论文  OAI收割 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 7 作者:  Zhang, Yuxuan;  Bonku, Emmanuel Mintah;  Yang, Xingbang;  Zhu, Fuqiang;  Jiang, Xiangrui   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/01/14 Direct reductive N-alkylation of amine  One-pot reaction  Grignard reagent  Amidation of ester  Cariprazine   Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 113, 页码: 5 作者:  Lu, Jie;  Cheng, Yan;  Zhang, Yumin;  Wang, Yi;  Xia, Bingqing   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/02/28 Bisbenzylisoquinoline alkaloid  Oxyacanthine derivatives  SARS-CoV-2   Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5 作者:  Shen, Wen;  Chen, Xinyao;  Zhou, Liping;  Cheng, Yan;  Zhang, Yan   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/10/21 COVID-19  SARS-CoV-2 3CL pro inhibitor  Drug design  Antiviral activities   Modular Combinatorial Development of Crystal-Glass Nano-Heterostructured Copper Alloys with Ultrahigh Strength and Large Deformability 期刊论文  OAI收割 ADVANCED FUNCTIONAL MATERIALS, 2024, 页码: 9 作者:  Zhou HB(周红波);  Yuan, Fusen;  Huang, Yao;  Wang, Yutian;  Bo, Zhenxing   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/11/01 amorphous/crystalline materials  combinatorial method  heterostructure  high strength  large deformability   Combination of miR159 Mimics and Irinotecan Utilizing Lipid Nanoparticles for Enhanced Treatment of Colorectal Cancer 期刊论文  OAI收割 PHARMACEUTICS, 2024, 卷号: 16, 期号: 4, 页码: 18 作者:  Yang, Rulei;  Liu, Yiran;  Yang, Ning;  Zhang, Tian;  Hou, Jiazhen   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/05/31 colorectal cancer  plant-derived miR159  irinotecan  lipid nanoparticle   Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4855-4869 作者:  Gu, Chenming;  Liu, Jiayuan;  Qian, Fei;  Yu, Wenchao;  Huang, Doudou   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/05/07 Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20 作者:  Yang, Wenjiao;  Gong, Xudong;  Sun, Haiguo;  Wu, Chunhui;  Suo, Jin   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/06 CB2R agonist  5-HT1AR agonist  CB1R antagonist  Antidepressant  Anxiolytic   Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19 期刊论文  OAI收割 NEW ENGLAND JOURNAL OF MEDICINE, 2024, 卷号: 390, 期号: 3, 页码: 230-241 作者:  Cao, Bin;  Wang, Yeming;  Lu, Hongzhou;  Huang, Chaolin;  Yang, Yumei   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/05/07