中国科学院机构知识库网格
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Impact of sub-Tg thermal cycling on the mechanical properties of CuZr metallic glasses: a molecular dynamics study
期刊论文
OAI收割
JOURNAL OF NON-CRYSTALLINE SOLIDS, 2025, 卷号: 668, 页码: 11
作者:
Khan, Arbaz
;
Zhao, Si-Jin
;
Qiao, Ji-Chao
;
Wang, Bing
;
Chazeau, Laurent
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/11/03
Metallic glasses
Thermal cycling
Molecular dynamics
Mechanical properties
Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24
作者:
Li, Na
;
Wang, Linlin
;
Hu, Xinyuan
;
Xu, Haiyan
;
Yang, Bowen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Voltage-gated sodium channel 1.8
Conformational restriction
Pharmacokinetic
Structure-activity relationship
Analgesic
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/07/28
Cytokine Storm Induction Linked to Multi-Organ Failure in Fatal Jellyfish Stings
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 页码: 12
作者:
Wang, Yichao
;
Wang, Yi
;
Yang, Fengling
;
Chen, Jingbo
;
Geng, Xiaoyu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/10/14
cytokine storm
envenomation
inflammation
jellyfish
NF-kappa B p65
Stable isotope tracing the transformation dynamics of diverse water bodies in the Manas River Basin, Northwest China
期刊论文
OAI收割
APPLIED WATER SCIENCE, 2025, 卷号: 15, 期号: 7, 页码: 156
作者:
Zhang, Heng
;
Tian, Lijun
;
Tian, Hao
;
Farid, Muhammad Arsalan
;
Li, Xiaolong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/07/18
Manas River Basin
Hydrogen and oxygen isotopes
Precipitation
Surface water
Groundwater
MixSIAR model
Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 15
作者:
Xu, Yali
;
Hu, Hao
;
Ran, Yu
;
Zhao, Wensi
;
Guo, An-Di
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Chemoproteomics
Molecular glue degraders
Photo-crosslinking
Protein-protein interactions
Targeted protein degradation
A bigel co-delivering highly hydrophilic and hydrophobic natural compounds for enhanced ulcerative colitis therapy
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 卷号: 678, 页码: 13
作者:
Wu, Yueqian
;
Jiang, Yuting
;
He, Yihao
;
Luo, Yanli
;
Gu, Zhiwen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Ulcerative colitis
Patchouli oil
Paeoniflorin
Bigel
Oral delivery
High-resolution Observational Features of Type I Solar Radio Bursts
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 985, 期号: 2
作者:
Yang, Yuzhi
;
Ning, Zongjun
;
Song, Yuxiang
;
Han, Yijie
;
Tang, Xiaoyu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/06/10
Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8
作者:
Wang, Shi-hang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/07/25
N
-methyl-
D
-aspartate receptors
GluN1/GluN3A
ligand-based virtual screening
scaffold hopping
deep learning
GeminiMol
Discovery of 3-(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 9864-9885
作者:
Hou, Hui
;
Zhou, Jingyi
;
Sui, Qibang
;
Zhang, Changfa
;
Su, Zhaoming
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/07/25