机构

• 上海药物研究所 [8]
• 生物物理研究所 [1]
• 新疆理化技术研究所 [1]
• 光电技术研究所 [1]

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2024 [1]
• 2023 [1]
• 2022 [3]
• 2021 [2]
• 2020 [1]
• 2016 [1]
• 更多

学科主题

• Biochemist... [1]

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13 作者:  Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu   |  收藏  |  浏览/下载：19/0  |  提交时间：2025/02/28 Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221 作者:  He Yifei;  Liu Yin;  Yu Jinghua;  Cheng Huan;  Odilov Abdullajon   |  收藏  |  浏览/下载：28/0  |  提交时间：2023/05/22 TPN171  14CTPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats 期刊论文  OAI收割 VASCULAR PHARMACOLOGY, 2022, 卷号: 145, 页码: 11 作者:  Zhao, Congke;  Hu, Liqing;  He, Xiangrong;  Li, Lijun;  Yin, Minghui   |  收藏  |  浏览/下载：62/0  |  提交时间：2022/08/16 Pulmonary hypertension  Hypoxia  Monocrotaline  Anti-inflammatory effects  NLRP3 inflammasome  Pulmonary artery endothelial cells   "One-Pot" Synthesis of Molnupiravir from Cytidine 期刊论文  OAI收割 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2022, 卷号: 26, 期号: 2, 页码: 358-364 作者:  Hu, Tianwen;  Xie, Yuanchao;  Zhu, Fuqiang;  Gong, Xudong;  Liu, Yin   |  收藏  |  浏览/下载：38/0  |  提交时间：2022/06/15 molnupiravir  cytidine  one-pot synthesis  DMF-DMA   "One-Pot" Synthesis of Molnupiravir from Cytidine 期刊论文  OAI收割 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2022, 卷号: 26, 期号: 2, 页码: 358-364 作者:  Hu, TW (Hu, Tianwen) [1] , [2];  Xie, YC (Xie, Yuanchao) [3];  Zhu, FQ (Zhu, Fuqiang) [4];  Gong, XD (Gong, Xudong) [4];  Liu, Y (Liu, Yin) [2] , [3]   |  收藏  |  浏览/下载：64/0  |  提交时间：2022/03/23 molnupiravir  cytidine  one-pot synthesis  DMF-DMA   Facile and Cost-Effective Route for the Synthesis of Simmerafil 期刊论文  OAI收割 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2432-2437 作者:  Odilov, Abdullajon;  Liu, Yin;  Hu, Tianwen;  Jiang, Xiangrui;  Suo, Jin   |  收藏  |  浏览/下载：51/0  |  提交时间：2022/01/18 simmerafil  PDE5 inhibitor  salicylamide  synthesis   Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 期刊论文  OAI收割 CELL RESEARCH, 2021, 页码: 3 作者:  Xie, Yuanchao;  Yin, Wanchao;  Zhang, Yumin;  Shang, Weijuan;  Wang, Zhen   |  收藏  |  浏览/下载：91/0  |  提交时间：2021/11/04 Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir 期刊论文  OAI收割 SCIENCE, 2020, 卷号: 368, 期号: 6498, 页码: 1499-+ 作者:  Yin, Wanchao;  Mao, Chunyou;  Luan, Xiaodong;  Shen, Dan-Dan;  Shen, Qingya   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/12/24 Synthesis, structure-activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychotics 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 13, 页码: 3141-3147 作者:  Yang, Feipu;  Jiang, Xiangrui;  Li, Jianfeng;  Wang, Yu;  Liu, Yongjian   |  收藏  |  浏览/下载：91/0  |  提交时间：2019/01/08 D-2  5-HT1A  5-HT2A  PCP-induced hyperactivity  Catalepsy   A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71 期刊论文  OAI收割 NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2012, 卷号: 19, 期号: 4, 页码: 424-429 Wang, Xiangxi; Peng, Wei; Ren, Jingshan; Hu, Zhongyu; Xu, Jiwei; Lou, Zhiyong; Li, Xumei; Yin, Weidong; Shen, Xinliang; Porta, Claudine; Walter, Thomas S; Evans, Gwyndaf; Axford, Danny; Owens, Robin; Rowlands, David J; Wang, Junzhi; Stuart, David I; Fry, Elizabeth E; Rao, Z 收藏  |  浏览/下载：28/0  |  提交时间：2013/12/24