中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
化学研究所 [8]
沈阳应用生态研究所 [6]
国家天文台 [5]
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期刊论文 [67]
会议论文 [2]
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2024 [1]
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Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS
期刊论文
OAI收割
XENOBIOTICA, 2024, 页码: 9
作者:
Yuan, Yali
;
Wang, Weiqiang
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/19
peptide-drug conjugate
PDC
LN005
metabolite identification
liver S9s
A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 11
作者:
Zhou, Ainan
;
Yu, Jinghua
;
Wu, Yali
;
Xue, Hao
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Monoclonal antibody
Bevacizumab
LC-MS
MS
Surrogate peptide
Pharmacokinetics
Serum
Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Rao, Danni
;
Yang, Tao
;
Feng, Huixu
;
An, Qi
;
Zhang, Shaofeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:
Wu, Feifei
;
Li, Huiyu
;
An, Qi
;
Sun, Yaoliang
;
Yu, Jinghua
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Hematopoietic progenitor kinase 1 (HPK1)
Cancer immunotherapy
Inhibitor
T cell
Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221
作者:
He Yifei
;
Liu Yin
;
Yu Jinghua
;
Cheng Huan
;
Odilov Abdullajon
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/05/22
TPN171
14CTPN171
PDE5 inhibitor
pulmonary arterial hypertension
healthy volunteers
pharmacokinetics
metabolite identification
mass balance
Dysmorphic appearance concern among Chinese adolescents and emerging adults
期刊论文
OAI收割
JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS, 2023, 卷号: 36, 页码: 9
作者:
Liu, Shuangshuang
;
Ma, Jinghua
;
Fan, Zhitao
;
Yu, Chaoran
;
Wang, Kui
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/03/01
Adolescents
Dysmorphic appearance concern
Emerging adults
Psychological distress
Place of residency
Unraveling the Therapeutic Mechanism of Saussurea involucrata against Rheumatoid Arthritis: A Network Pharmacology and Molecular Modeling-Based Investigation
期刊论文
OAI收割
NUTRIENTS, 2023, 卷号: 15, 期号: 19
作者:
Chen, Jinghua
;
Wu, Xiaoke
;
Yu, Ruitao
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/01
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1 beta and IL-6
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4180-4192
作者:
Liao, Liping
;
Dang, Wenzhen
;
Lin, Tingting
;
Yu, Jinghua
;
Liu, Tonghai
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Glycolysis
Phosphoglycerate kinase 1
Macrophages
NRF2
Inflammation
Science Goals of the Earth 2.0 Space Mission
会议论文
OAI收割
Montreal, CANADA, JUL 17-22, 2022
作者:
Zhang, Hui
;
Ge, Jian
;
Deng, Hongping
;
Yao, Xinyu
;
Zhu, Jiapeng
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/06/28
ET
Earth 2.0
terrestrial planet
habitable planet
free-floating
planet
time-domain
black-hole
binary stars
ET White Paper: To Find the First Earth 2.0
预印本
OAI收割
2022
作者:
Ge, Jian
;
Zhang, Hui
;
Zang, Weicheng
;
Deng, Hongping
;
Mao, Shude
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/07/29