中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
高能物理研究所 [20]
大连化学物理研究所 [14]
合肥物质科学研究院 [13]
上海药物研究所 [12]
生态环境研究中心 [12]
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期刊论文 [221]
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EI期刊论文 [2]
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2024 [7]
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Physics [5]
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Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 277, 页码: 17
作者:
Zhuang, Zhen
;
Miao, Yu-Ling
;
Song, Shan-Shan
;
Leng, Guang-Tong
;
Zhang, Xiao-Fei
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/09/26
USP7 inhibitor
Structure-activity relationships
Anti-cancer
pyrrolo[2,3-d]pyrimidin-4-one
Talaketides A-G, linear polyketides with prostate cancer cytotoxic activity from the mangrove sediment-derived fungus Talaromyces sp. SCSIO 41027
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2024, 卷号: 22, 期号: 11, 页码: 1047-1056
作者:
Chen, Chunmei
;
Wang, Xueni
;
Fang, Wenxuan
;
Liang, Jiaqi
;
Cai, Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/12/11
[KEY WORDS] Mangrove sediment-derived fungus
Talaromyces sp.
Linear polyketides
Cytotoxicity
Prostate cancer.
Global marine microbial diversity and its potential in bioprospecting
期刊论文
OAI收割
NATURE, 2024, 页码: 27
作者:
Chen, Jianwei
;
Jia, Yangyang
;
Sun, Ying
;
Liu, Kun
;
Zhou, Changhao
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/10/21
Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 21
作者:
Lu, Yang
;
Gao, Jian
;
Wang, Peipei
;
Chen, Haifeng
;
He, Xinjun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/07/12
Hepatocellular carcinoma
Ubiquitin-specific protease 10
Deubiquitination
Selectivity
The demise of the giant ape
Gigantopithecus blacki
期刊论文
OAI收割
NATURE, 2024, 卷号: 625, 期号: 7995, 页码: 25
作者:
Zhang, Yingqi
;
Westaway, Kira E.
;
Haberle, Simon
;
Lubeek, Julien K.
;
Bailey, Marian
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/05/11
Secure FSO communication based on optical frequency-hopping technology using delay interferometers
期刊论文
OAI收割
Optics Communications, 2024, 卷号: 550
作者:
Wang, Jian
;
Jin, Ya
;
Xie, Zhuang
;
Chen, Yinfang
;
Liu, Yu
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2023/10/13
Optical delay interferometers
Optical frequency hopping
Physical layer security
FSO communications
A kinetics-coupled multi-surface complexation model deciphering arsenic adsorption and mobility across soil types
期刊论文
OAI收割
Science of The Total Environment, 2024, 卷号: 948, 页码: 174856
作者:
Yutong Liu
;
Liyang Zhang
;
Yubo Wen
;
Hanzhao Zhai
;
Yuli Yuan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/03/27
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
The distribution and emission of CO2, CH4 and light hydrocarbons in an anticyclonic eddy of the Kuroshio extension
期刊论文
OAI收割
FRONTIERS IN MARINE SCIENCE, 2023, 卷号: 10, 页码: 13
作者:
Li, Xiao-Jun
;
Wang, Jian
;
Qiao, Hao
;
Zhu, Rui-Chen
;
Zhang, Hong-Hai
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/12/07
mesoscale eddy
Kuroshio and Oyashio Extension (KOE)
climate-relevant gases
air-sea fluxes
CO2
methane
non-methane hydrocarbons
Selective Covalent Targeting of Pyruvate Kinase M2 Using Arsenous Warheads
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 4, 页码: 2608-2621
作者:
Wang, Jingyao
;
Zhou, Shaoqing
;
Cheng, Yan
;
Cheng, Lin
;
Qin, Ying
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/03/27