中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [139]
沈阳应用生态研究所 [13]
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期刊论文 [207]
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Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth
期刊论文
OAI收割
MOLECULES, 2025, 卷号: 30, 期号: 10, 页码: 22
作者:
Peng, Xia
;
Yu, Siqi
;
Xu, Lin
;
Wang, Qinghua
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/07/25
pseudolaric acid B
amide derivatives
tumor-associated macrophages
anti-tumor
repolarization
Discovery of Potent STING Inhibitors Bearing a Difluorobenzodioxol Structural Motif as Potent Anti-Inflammatory Agents
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8907-8932
作者:
Shen, Ancheng
;
Wang, Xiyuan
;
Chen, Qingxuan
;
Zhang, Yan
;
Wang, Fang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/05/27
Comparison and integration of hydrological models and machine learning models in global monthly streamflow simulation
期刊论文
OAI收割
JOURNAL OF HYDROLOGY, 2025, 卷号: 650, 页码: 17
作者:
Zhang, Jiawen
;
Kong, Dongdong
;
Li, Jianfeng
;
Qiu, Jianxiu
;
Zhang, Yongqiang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/03/31
Streamflow simulation
Machine learning
Hydrological model
Multi-model weighting ensemble
Quantitation of global histone post-translational modifications reveal anti-inflammatory epigenetic mechanisms of liquiritigenin based on the optimized super-SILAC strategy
期刊论文
OAI收割
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2025, 卷号: 13, 页码: 15
作者:
Liu, Ping
;
Zhang, Jun
;
Zhang, Jingdan
;
Yuan, Yucheng
;
Liu, Zhiqing
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/05/27
histone post-translational modifications
super-SILAC
liquiritigenin
inflammation
epigenetics
PPAR
Discovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect
期刊论文
OAI收割
MEDCOMM, 2025, 卷号: 6, 期号: 1, 页码: e70001
作者:
Wang, Xiyuan
;
Zhan, Zhengsheng
;
Wang, Zhen
;
Zhang, Yan
;
Zhao, Kaiyan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/06/04
antitumor
immune memory
innate immunity
STING agonist
Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13
作者:
Tang, Mingze
;
Zhou, Xuan
;
Shen, Qianqian
;
Fang, Chen
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/08/22
Receptor -interacting protein kinase 1
Histone deacetylases
Inhibitor
Molecular dynamics (MD) simulation
ADMET analysis
Design and synthesis of pyridazin-4-one derivatives as necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 16
作者:
An, Yuxiang
;
Peng, Xia
;
Wang, Tianchen
;
Liu, Kaiyuan
;
Feng, Dazhi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/12/25
inhibitor
pharmacokinetic study
pyridazin-4-one
receptor-interacting protein kinase 1
selectivity
Sodium oligomannate disrupts the adherence of Rib
high
bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19
作者:
Wang, Xinyi
;
Xie, Zuoquan
;
Yuan, Jie
;
Jin, Enjing
;
Lian, Wen
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/12/16
Seesaw between the westerlies and Asian monsoon regulates vegetation and climate during the last deglaciation in southern Northeast China
期刊论文
OAI收割
QUATERNARY SCIENCE REVIEWS, 2024, 卷号: 344, 页码: 13
作者:
Wang, Jian
;
Zhang, Guilin
;
Zhang, Wenchao
;
Zhou, Xinying
;
Liu, Junchi
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/06/11
Last deglaciation
Northeast China
Vegetation
East Asian monsoon
Westerly
A DXd/TLR7-Agonist Dual-Conjugate Anti-HER2 ADC Exerts Robust Antitumor Activity Through Tumor Cell Killing and Immune Activation
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2024, 卷号: 23, 期号: 11, 页码: 1639-1651
作者:
Yue, Hangtian
;
Xu, Hui
;
Ma, Lanping
;
Li, Xiyuan
;
Yang, Biyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/12/11