中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [94]
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Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
Zeng, Yanping
;
Xiao, Jian
;
Shi, Li
;
Li, Yangsha
;
Xu, Yuanxin
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
CXCR2 modulates chronic pain comorbid depression in mice by regulating adult neurogenesis in the ventral dentate gyrus
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13
作者:
Li, Xiao-jie
;
Wu, Shuo
;
Liu, Zi-han
;
Liu, An-an
;
Peng, Hui-sheng
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
chronic pain comorbid depression
adult neurogenesis
dentate gyrus
CXCR2
Wnt3a/beta-catenin pathway
Cryo-Shocked Tumor-Reprogrammed Sonosensitive Antigen-Presenting Cells Improving Sonoimmunotherapy via T Cells and NK Cells Immunity
期刊论文
OAI收割
ADVANCED MATERIALS, 2025, 页码: 17
作者:
Qian, Xindi
;
Yi, Wenzhe
;
Yan, Wenlu
;
Cai, Ying
;
Hu, Shuangshuang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
adaptive immunity
antigen presentation
innate immunity
sonoimmunotherapy
tumor cell reprogramming
Exploratory research on the effective chemical basis of tanreqing injection for treating acute lung injury: In vivo, in vitro and in silico
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 337, 页码: 11
作者:
Tang, Bixi
;
Xie, Like
;
Wang, Yangyang
;
Shi, Yulong
;
Kan, Weijuan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/11/26
Lung first-pass effect
Tanreqing injection
Pharmacokinetics
Sepsis-associated acute lung injury
Acute respiratory distress syndrome
Uncommon Diterpenoids with Diverse Frameworks from the South China Sea Sponge
Spongia officinalis
and Their Anti-inflammatory Activities
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2025, 卷号: 90, 期号: 5, 页码: 1950-1956
作者:
Li, Song-Wei
;
Liu, Jiao
;
Liu, Zi-Yi
;
Fu, Yan
;
Yao, Li-Gong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Structural insights into the agonist activity of the nonpeptide modulator JR14a on C3aR
期刊论文
OAI收割
CELL DISCOVERY, 2025, 卷号: 11, 期号: 1, 页码: 4
作者:
Luo, Ping
;
Xin, Wenwen
;
Guo, Shimeng
;
Li, Xin
;
Zhang, Qing
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/01
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
Preclinical Evaluation and Pilot Clinical Study of CD137 PET Radiotracer for Noninvasive Monitoring Early Responses of Immunotherapy
期刊论文
OAI收割
JOURNAL OF NUCLEAR MEDICINE, 2025, 卷号: 66, 期号: 1, 页码: 40-46
作者:
Cheng, Kai
;
Ge, Luna
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/01
PET imaging
CD137
activated T cells
immunotherapy
Personalized Multi-Epitope Nanovaccine Unlocks B Cell-Mediated Multiple Pathways of Antitumor Immunity
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 19
作者:
Yan, Wenlu
;
Cao, Ying
;
Xu, Shanshan
;
Li, Yu
;
Wu, Ting
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/02/28
B lymphocytes
cellular immunity
humoral immunity
nanovaccine
tumor immunotherapy