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Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12
作者:
Wu, Feifei
;
Sun, Jiaqi
;
Xu, Mingyang
;
Li, Huiyu
;
Wei, Jiarui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Macrocycle
Kinase
Inhibitors
HPK1
Cancer immunotherapy
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/07/28
The dynamic features and microbial mechanism of nitrogen transformation in small greenhouse farming system of Pacific white shrimp,
Litopenaeus vannamei
期刊论文
OAI收割
AQUACULTURE, 2025, 卷号: 605, 页码: 14
作者:
Huang, Yong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/07/11
Small greenhouse farming system
Denitrification
Nitrification
Surface sediment
Suspended particulate matter
The Chinese Pulsar Timing Array Data Release I Single pulsar noise analysis
期刊论文
OAI收割
ASTRONOMY & ASTROPHYSICS, 2025, 卷号: 699
作者:
Chen, Siyuan
;
Xu, Heng
;
Guo, Yanjun
;
Wang, Bojun
;
Caballero, R. Nicolas
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/07/21
gravitational waves
methods: data analysis
pulsars: general
The Overview and Trial Observations of AIMS
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Deng, Yuanyong
;
Wang, Dongguang
;
Hua, Jianwen
;
Xu, Songbo
;
Liang, Ming
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/07/14
Sun: infrared
methods: observational
instrumentation: spectrographs
中国式现代化背景下自然保护地体系建设的新理论、新方法与法制保障
期刊论文
OAI收割
自然资源学报, 2025, 卷号: 40, 期号: 06, 页码: 1429-1450
作者:
蔡晓梅
;
苏杨
;
徐卫华
;
周绍杰
;
何思源
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/07/04
Chinese modernization
nature reserves
national parks
harmonious coexistence between human beings and nature
new quality productive forces
collaborative governance
Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth
期刊论文
OAI收割
MOLECULES, 2025, 卷号: 30, 期号: 10, 页码: 22
作者:
Peng, Xia
;
Yu, Siqi
;
Xu, Lin
;
Wang, Qinghua
;
Yang, Lin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/07/25
pseudolaric acid B
amide derivatives
tumor-associated macrophages
anti-tumor
repolarization
Unveiling p65 as the target of diphyllin in ameliorating metabolic dysfunction-associated steatotic liver disease via targeted protein degradation technology
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2025, 卷号: 16, 页码: 12
作者:
Zhu, Xuejing
;
Zhang, Lei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/07/25
metabolic dysfunction-associated steatotic liver disease
diphyllin
p65
targeted protein degradation technology
NRF2
Development of
99m
Tc-labeled melanin-targeted probes for SPECT imaging of melanoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2025, 页码: 14
作者:
Tao, Ji
;
Cao, Rui
;
Lei, Zhe
;
Wang, Xiao
;
Luo, Renli
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/06/23
Melanoma
Melanin
(99m)Technetium
SPECT
Imaging probe
Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796
作者:
Hu, Liuyan
;
Zhao, Zhi
;
Zhang, Shujing
;
Yang, Lei
;
Cui, Wenjie
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/06/23
COVID-19
SARS-CoV-2
3CL protease
Peptidomimetic inhibitors
Tetrahydropyrrole spirodihydroindolone