中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
自动化研究所 [15]
上海药物研究所 [10]
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OAI收割 [34]
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期刊论文 [19]
会议论文 [15]
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2025 [2]
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Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10
作者:
Yu, Qian
;
Gao, Lixin
;
Xu, Linhao
;
Han, Yubing
;
Cao, Yu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/11
Zero-Shot Cross-Lingual Document-Level Event Causality Identification with Heterogeneous Graph Contrastive Transfer Learning
会议论文
OAI收割
Torino, Italia, 2024-5
作者:
Zhitao He
;
Pengfei Cao
;
Zhuoran Jin
;
Yubo Chen
;
Kang Liu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/06/25
Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 17
作者:
Yu, Qian
;
Wang, Zheng
;
Tu, Yutong
;
Cao, Yu
;
Zhu, Huajian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/07
20S proteasome
Proteasome activation
IDPs
Undruggable
Protein homeostasis
Electric field as extracellular enzyme activator promotes conversion of lignocellulose to humic acid in composting process
期刊论文
OAI收割
BIORESOURCE TECHNOLOGY, 2024, 卷号: 391, 页码: 10
作者:
Zhang, Lu
;
Wang, Xuan
;
Wang, Hongge
;
Cao, Yubo
;
Weng, Liping
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/01/02
Bioconversion
Carbon conversion
Humification
Bioelectrochemical assistance
Lignocellulose degradation
Leros: Learning Explicit Reasoning on Synthesized Data for Commonsense Question Answering
会议论文
OAI收割
Torino, Italia, 2024-5
作者:
Wang, Chenhao
;
Cao, Pengfei
;
Li, Jiachun
;
Chen, Yubo
;
Liu, Kang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/05/30
MULFE: A Multi-Level Benchmark for Free Text Model Editing
会议论文
OAI收割
Bangkok, Thailand, 2024-08
作者:
Wang, Chenhao
;
Cao, Pengfei
;
Jin, Zhuoran
;
Chen, Yubo
;
Zeng, Daojian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/06/25
LEGO: A Multi-agent Collaborative Framework with Role-playing and Iterative Feedback for Causality Explanation Generation
会议论文
OAI收割
Singapore, 2023-12
作者:
Zhitao He
;
Pengfei Cao
;
Yubo Chen
;
Kang Liu
;
Jun Zhao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/06/25
Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 138, 页码: 22
作者:
Wang, Hanlin
;
Wu, Zhaoxiao
;
Cao, Yu
;
Gao, Lixin
;
Shao, Jiaan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Metabolic stability
Four-membered heterocycles
Proteasome inhibitors
Multiple myeloma