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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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地理科学与资源研... [114]
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/ NF-κB/MLCK/MLC signaling in ulcerative colitis
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2025, 卷号: 162, 页码: 12
作者:
Zhou, Ruochen
;
Cui, Yuanyuan
;
Wang, Weihao
;
Qu, Yidan
;
Zhang, Gaojie
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Ubiquitin-specific protease 2
Ulcerative colitis
Intestinal epithelial cell
Tight junction
Human gut
Bifidobacterium longum
subsp.
suillum
is enriched in vitro by a pectic polysaccharide isolated from the flowers of
Lilium lancifolium
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2025, 卷号: 364, 页码: 14
作者:
Li, Meixia
;
Liu, Renjie
;
Wang, Tao
;
Duo, Lana
;
Chen, Guo
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Polysaccharides
Lilium lancifolium
Human gut microbiota
Bifidobacterium longum subsp. suillum
Screening and functional characterization of nanobodies targeting the transferrin receptor
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2025, 卷号: 231, 页码: 7
作者:
Ding, Yuting
;
Jia, Li
;
Geng, Qifubo
;
Liu, Yan
;
Guo, Shaojue
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/05/27
Transferrin receptor (TfR1)
Nanobody screening
Cancer therapy
Enhanced Bioactivity of Natural Products by Halogenation: A Database Survey and Quantum Chemistry Calculation Study
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 10486-10496
作者:
Cao, Ruini
;
Li, Jintian
;
Liao, Qingyi
;
Shao, Mei
;
Zhang, Qian
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/07/25
Comprehensive Metabolite Profiling in Single-Cell Systems via Dual-Modal MALDI-Mass Spectrometry Imaging
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2025, 卷号: 97, 期号: 16, 页码: 8729-8737
作者:
Yuan, Jie
;
Li, Xiafei
;
Shen, Xinxin
;
Xiong, Pei
;
Zhu, Nanlin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/06/23
Chemoenzymatic liquid-phase synthesis and immunogenic assessment of tumor-associated complex MUC1 glycopeptide variants
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 302, 页码: 11
作者:
Teng, Changcai
;
Ma, Wenjing
;
Liu, Jinfeng
;
Hou, Juan
;
Zhang, Yalong
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/04/01
MUC1 glycopeptide conjugate
Liquid phase glycopeptide synthesis
Immunological evaluations
A High-Precision Method for Determining Elastic Parameters in Hard Rock Using Cellular Automata and Simulated Annealing Particle Swarm Optimization
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF APPLIED MECHANICS, 2025, 卷号: 17, 期号: 04, 页码: 28
作者:
Zhao, Xiaoxun
;
Pan, Peng-Zhi
;
Wang, Zhaofeng
;
Wang, Wei
;
Hekmatnejad, Amin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/06/27
Digital image correlation
cellular automata
simulated annealing particle swam optimization
eccentric loading
elastic properties
Quantitation of global histone post-translational modifications reveal anti-inflammatory epigenetic mechanisms of liquiritigenin based on the optimized super-SILAC strategy
期刊论文
OAI收割
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2025, 卷号: 13, 页码: 15
作者:
Liu, Ping
;
Zhang, Jun
;
Zhang, Jingdan
;
Yuan, Yucheng
;
Liu, Zhiqing
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/05/27
histone post-translational modifications
super-SILAC
liquiritigenin
inflammation
epigenetics
PPAR
Synthesis and Evaluation of Optical Properties, SHP2 Inhibitory Activity, and Cellular Imaging for Novel 2-Quinolone Derivatives
期刊论文
OAI收割
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2025, 页码: 10
作者:
Zhang, Chun
;
Yang, Yuting
;
Gao, Li-Xin
;
Gan, Suya
;
Li, Jia
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2025/05/27
Fluorescent inhibitors
SHP2
2-quinolone derivatives
optical properties
drug tracing
medical diagnosis