中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
上海微系统与信息技术... [2]
武汉植物园 [2]
植物研究所 [2]
上海营养与健康研究所 [1]
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OAI收割 [16]
内容类型
期刊论文 [15]
专利 [1]
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2025 [3]
2024 [4]
2023 [2]
2018 [1]
2017 [2]
2015 [2]
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Agricultur... [1]
Agronomy [1]
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Screening of botanical drugs reveals the potential anti-human adenovirus activity of berberine
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2025, 卷号: 237, 页码: 9
作者:
Cao, Junyuan
;
Zhang, Hao
;
Zhang, Jixiang
;
Wang, Jinlin
;
Li, Chen
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
Human adenovirus
Antiviral drug
Berberine
High-throughput screening
Design and Development of a Novel Oral 4′-Fluorouridine Double Prodrug VV261 against SFTSV
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 9, 页码: 9811-9826
作者:
Cheng, Yong
;
Zheng, Wei
;
Dong, Xinru
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 页码: 13
作者:
Su, Haixia
;
Wu, Guoqing
;
Xiong, Muya
;
Wang, Yuhang
;
Cao, Junyuan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/27
covalent inhibitors
I7L protease
monkeypox virus
protein structures
substrate proteolysis
Discovery of novel small molecules targeting hepatitis B virus core protein from marine natural products with HiBiT-based high-throughput screening
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 4914-4933
作者:
Huang, Chao
;
Jin, Yang
;
Fu, Panpan
;
Hu, Kongying
;
Wang, Mengxue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/01/06
Anti-HBV
HBV core protein
Core protein assembly modulators
Marine natural products
HiBiT
Lead compound
Naamidine J derivative
Bioactivity-driven synthesis
Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CL
pro
Inhibitors as anti-SARS-CoV-2 Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783
作者:
Jiang, Zhidong
;
Feng, Bo
;
Chen, Lu
;
Nie, Tianqing
;
Chen, Shizhao
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/09/26
SARS-CoV-2 envelope protein-derived extracellular vesicles act as potential media for viral spillover
期刊论文
OAI收割
JOURNAL OF MEDICAL VIROLOGY, 2024, 卷号: 96, 期号: 7, 页码: 11
作者:
Li, Shuangqu
;
Bu, Jiwen
;
Pan, Xiaoyan
;
Li, Qiguang
;
Zuo, Xiaoli
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/09/26
cellular signal transduction
coronavirus
cytokine/chemokine
immune responses
research and analysis methods
virus classification
Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290
作者:
Zheng, Miao
;
Feng, Bo
;
Zhang, Yumin
;
Liu, Xin
;
Zhao, Na
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/08/22
Non-covalent PLpro inhibitors
Antiviral activity
Structural-based drug design
Imidazo[4,5-b]pyridine scaffold
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Jiang, Xiangrui
;
Su, Haixia
;
Shang, Weijuan
;
Zhou, Feng
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2024/03/25
Multiplication of defective Ebola virus in a complementary permissive cell line
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2023, 卷号: 209, 页码: 8
作者:
Tong, Xian-Kun
;
Li, Heng
;
Yang, Li
;
Xie, Shi-Zhe
;
Xie, Sha
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/04/10
Recently Evolved Tumor Suppressor Transcript TP73-AS1 Functions as Sponge of Human-Specific miR-941
期刊论文
OAI收割
MOLECULAR BIOLOGY AND EVOLUTION, 2018, 卷号: 35, 期号: 5, 页码: 1063-1077
作者:
Hu, Haiyang
;
Jiang, Xi
;
Yang, Xiaode
;
Liu, Jian-Mei
;
Hu, Zhenyu
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/09
microRNA sponge
young noncoding RNA
co-evolution
tumorigenesis