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浏览/检索结果: 共668条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11 作者:  Guma, Samuel Desta;  Song, Kang;  Sun, Haiguo;  Yang, Lei;  Zhou, Zhaoyin   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 SARS-CoV-2  3CL(pro) inhibitors  Thioamide derivatives  Spiropyrrolidine derivatives  Nirmatrelvir  HCoV-OC43  Antiviral  Metabolic stability   Structural optimization of phthalazine derivatives for anti-HBV activities to improve oral bioavailability 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 10 作者:  Yang, Yurong;  Xiao, Fuling;  Zuo, Jianping;  Yang, Li;  Hu, Youhong   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 HBV  Capsid assembly modulators  Structural optimization  Oxidative metabolism   Discovery of potent anti-idiopathic pulmonary fibrosis (IPF) agents based on an o-aminopyridinyl alkynyl scaffold 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 15 作者:  Wang, Yang;  Fan, Wenhui;  Guo, Yihao;  Sun, Li;  Hu, Youhong   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/08/20 IPF  EMT  Key kinases  Inhibitors   Immunosuppressive nitrogen-containing triterpenoid saponins from Mussaenda erosa and the therapeutic efficacy of heinsiagenin A in a murine lupus erythematosus model 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 11 作者:  Xu, Yidan;  Xiang, Mai;  Chang, Yuan;  Chen, Zhenhua;  Zhang, Rujun   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Mussaenda erosa  Nitrogen-containing triterpenoid saponins  Immunosuppressive activity  Autoimmune diseases  Heinsiagenin A   Spectroastrometry and Reverberation Mapping of Active Galactic Nuclei. II. Measuring Geometric Distances and Black Hole Masses of Four Nearby Quasars 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1 作者:  Li, Yan-Rong;  Shangguan, Jinyi;  Wang, Jian-Min;  Davies, Ric;  Santos, Daryl J. D.   |  收藏  |  浏览/下载：24/0  |  提交时间：2025/07/21 Diterpenoids and diarylheptanoids from the fruits of Alpinia zerumbet and their anti-inflammatory activity 期刊论文  OAI收割 FITOTERAPIA, 2025, 卷号: 184, 页码: 10 作者:  Zhang, Zhenghan;  Li, Guangqian;  Luo, Xin   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Alpinia zerumbet  Labdane-type diterpenoid  Diarylheptanoid  Anti-inflammatory  ISG pathway  TDDFT ECD calculation   Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2025, 卷号: 17, 期号: 801, 页码: 18 作者:  Yang, Ruirui;  Wang, Bei;  Su, Zhaoming;  Song, Ying;  Zhang, Yingying   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/08/20 Monitoring AGNs with Hβ Asymmetry. V. Long-term Variation and Evolution of the Broad Hβ Emission-line Profiles 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2025, 卷号: 278, 期号: 2 作者:  Fang, Feng-Na;  Du, Pu;  Brotherton, Michael S.;  McLane, Jacob N.;  Zastrocky, T. E.   |  收藏  |  浏览/下载：28/0  |  提交时间：2025/06/10 Supermassive Black Holes with High Accretion Rates in Active Galactic Nuclei. XIV. Long-duration High-cadence Reverberation Mapping Results for 11 PG Quasars 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2025, 卷号: 278, 期号: 2 作者:  Hu, Chen;  Yao, Zhu-Heng;  Chen, Yong-Jie   |  收藏  |  浏览/下载：22/0  |  提交时间：2025/06/23 An Asymmetric Reductive Amination Synthesis of Ritlecitinib Using (S)-α-Methylbenzylamine as Chiral Auxiliary 期刊论文  OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2025, 页码: 10 作者:  Dong, Hongkun;  Bonku, Emmanuel Mintah;  Zhang, Yuxuan;  Yang, Xingbang;  Abduahadi, Safomuddin   |  收藏  |  浏览/下载：20/0  |  提交时间：2025/07/25 asymmetric reductive amination  chiral auxiliary  intramolecular amide formation  ritlecitinib  delta-lactam