中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共55条,第1-10条 帮助

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Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:  
Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong
  |  收藏  |  浏览/下载:4/0  |  提交时间:2025/06/23
Discovery of multi-chitinase inhibitors cinnamyl thiazolidinone compounds as candidates for insect growth regulators via ligand-based optimization strategies 期刊论文  OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 306, 页码: 14
作者:  
Jiang, Zhiyang;  Shi, Dongmei;  Fu, Haoyu;  Li, Yan;  Zou, Renxuan
  |  收藏  |  浏览/下载:3/0  |  提交时间:2025/05/27
Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796
作者:  
Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie
  |  收藏  |  浏览/下载:1/0  |  提交时间:2025/06/23
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:  
Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin
  |  收藏  |  浏览/下载:17/0  |  提交时间:2024/12/11
F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13
作者:  
Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu
  |  收藏  |  浏览/下载:19/0  |  提交时间:2025/02/28
Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16
作者:  
Zheng, Jiefang
  |  收藏  |  浏览/下载:14/0  |  提交时间:2024/08/22
Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16
作者:  
Li, Xiaomei;  Zhang, Hui;  Dong, Sanfeng;  Gao, Xuejie;  Sun, Haiguo
  |  收藏  |  浏览/下载:34/0  |  提交时间:2024/09/26
Histopathological bladder cancer gene mutation prediction with hierarchical deep multiple-instance learning 期刊论文  OAI收割
MEDICAL IMAGE ANALYSIS, 2023, 卷号: 87, 页码: 13
作者:  
Yan, Rui;  Shen, Yijun;  Zhang, Xueyuan;  Xu, Peihang;  Wang, Jun
  |  收藏  |  浏览/下载:29/0  |  提交时间:2023/12/04
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2 期刊论文  OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 5, 页码: 2384-2391
作者:  
Xu, Zhijian;  Shi, Danrong;  Han, Jianbao;  Ling, Yun;  Jiang, Xiangrui
  |  收藏  |  浏览/下载:42/0  |  提交时间:2024/03/27
Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 14
作者:  
Sun, Haiguo;  Xi, Mengyu;  Jin, Qiang;  Zhu, Zhengdan;  Zhang, Yani
  |  收藏  |  浏览/下载:56/0  |  提交时间:2022/09/30