中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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地理科学与资源研究... [89]
植物研究所 [40]
生态环境研究中心 [37]
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期刊论文 [356]
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/ NF-κB/MLCK/MLC signaling in ulcerative colitis
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2025, 卷号: 162, 页码: 12
作者:
Zhou, Ruochen
;
Cui, Yuanyuan
;
Wang, Weihao
;
Qu, Yidan
;
Zhang, Gaojie
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Ubiquitin-specific protease 2
Ulcerative colitis
Intestinal epithelial cell
Tight junction
Human gut
Bifidobacterium longum
subsp.
suillum
is enriched in vitro by a pectic polysaccharide isolated from the flowers of
Lilium lancifolium
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2025, 卷号: 364, 页码: 14
作者:
Li, Meixia
;
Liu, Renjie
;
Wang, Tao
;
Duo, Lana
;
Chen, Guo
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Polysaccharides
Lilium lancifolium
Human gut microbiota
Bifidobacterium longum subsp. suillum
Gastrodia elata
Blume extract alleviates sepsis-induced lung injury by suppressing IL-23/IL-17 A axis
期刊论文
OAI收割
FITOTERAPIA, 2025, 卷号: 184, 页码: 12
作者:
Dong, Huiqing
;
Zhang, Yun
;
Zhou, Yang
;
Zhang, Menghui
;
Zhang, Lei
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Gastrodia elata Blume extract
Sepsis-induced lung injury
IL-23/IL-17 A axis
Neutrophil infiltration
Bacterial Membrane Vesicles as Heteroantigen Reservoirs for Potentiated Colorectal Cancer Immunotherapy
期刊论文
OAI收割
ACS NANO, 2025, 卷号: 19, 期号: 26, 页码: 23760-23777
作者:
Liu, Chang
;
Yang, Canyu
;
Jiang, Xiuxian
;
Lu, Xiang
;
Huang, Xiaoyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
immunotherapy
bacterial membrane vesicle
heteroantigen reservoir
PD-L1 siRNA
immune checkpointblockade
Small-Molecule Probe [
68
Ga]Ga-SMIC-2501 Targeting the V-Domain Immunoglobulin Suppressor of T Cell Activation Protein for Positron Emission Tomography Imaging
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2025, 页码: 11
作者:
Wang, Gang
;
Cao, Rui
;
Liu, Shumei
;
Qian, Kun
;
Sun, Luming
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
VISTA
immunecheckpoint
immunotherapy
PET
tumor microenvironment
molecular imaging
Systematic optimization of prime editing for enhanced efficiency and versatility in genome engineering across diverse cell types
期刊论文
OAI收割
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2025, 卷号: 13, 页码: 13
作者:
Mu, Huiling
;
Liu, Yeyi
;
Chi, Yijia
;
Wang, Fei
;
Meng, Shuting
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/07/25
prime editing
piggyBac transposon system
pluripotent stem cells
sustained expression
genome engineering
Satellite observed rapid inland aquaculture expansion in Jianghan Plain, China from 2016 to 2022
期刊论文
OAI收割
AQUACULTURE, 2025, 卷号: 599, 页码: 742132
作者:
Wang, Chen
;
Dong, Jinwei
;
Zhou, Yan
;
Cui, Yifeng
;
Chen, Xi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/03/18
Inland freshwater aquaculture
Rice-crayfish fields
Google earth engine
Jianghan Plain
Spatial-temporal variation pattern
Chemoenzymatic liquid-phase synthesis and immunogenic assessment of tumor-associated complex MUC1 glycopeptide variants
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 302, 页码: 11
作者:
Teng, Changcai
;
Ma, Wenjing
;
Liu, Jinfeng
;
Hou, Juan
;
Zhang, Yalong
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/04/01
MUC1 glycopeptide conjugate
Liquid phase glycopeptide synthesis
Immunological evaluations
A High-Precision Method for Determining Elastic Parameters in Hard Rock Using Cellular Automata and Simulated Annealing Particle Swarm Optimization
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF APPLIED MECHANICS, 2025, 卷号: 17, 期号: 04, 页码: 28
作者:
Zhao, Xiaoxun
;
Pan, Peng-Zhi
;
Wang, Zhaofeng
;
Wang, Wei
;
Hekmatnejad, Amin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/06/27
Digital image correlation
cellular automata
simulated annealing particle swam optimization
eccentric loading
elastic properties