机构

• 上海药物研究所 [17]
• 半导体研究所 [10]
• 广州地球化学研究所 [3]
• 兰州化学物理研究所 [3]
• 深圳先进技术研究院 [2]
• 化学研究所 [2]
• 更多

采集方式

• OAI收割 [42]
• iSwitch采集 [1]

内容类型

• 期刊论文 [40]
• 专利 [3]

发表日期

• 2025 [1]
• 2024 [4]
• 2023 [5]
• 2022 [1]
• 2021 [4]
• 2020 [9]
• 更多

学科主题

• 光学与环境监测遥感技... [1]

筛选

浏览/检索结果: 共43条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19 作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/04/01 Acute myeloid leukemia  HDAC inhibitor  FLT3-ITD mutation  DNA damage response  Synergistic effect  Drug resistance   Tumor-specific delivery of clickable inhibitor for PD-L1 degradation and mitigating resistance of radioimmunotherapy 期刊论文  OAI收割 SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 46, 页码: 17 作者:  Hou, Bo;  Ye, Jiayi;  Huang, Lujia;  Cheng, Wenhao;  Chen, Fangmin   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/12/16 Synthesis and biological evaluation of 4-imidazolidinone-containing compounds as potent inhibitors of the MDM2/p53 interaction 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 270, 页码: 16 作者:  Lin, Zhitong;  Liu, Chen;  Yan, Ziqin;  Cheng, Jing;  Wang, Xiancheng   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/06/27 MDM2  p53  p21  Imidazolidinone  Apoptosis   Toxicity and chemical characterization of shale gas wastewater discharged to the receiving water: Evidence from toxicity identification evaluation 期刊论文  OAI收割 SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 912, 页码: 12 作者:  Zhou, Zhimin;  Wu, Fan;  Tong, Yujun;  Zhang, Shaoqiong;  Li, Liang   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/09/12 Hydraulic fracturing  Flowback and produced water  TIE  Ecological risk from mixtures  Non-target analysis  Organismal uptake   Structure-based optimization of indoline-containing compounds as second generation inhibitors of NF-KB-inducing kinase (NIK) 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1295, 页码: 19 作者:  Cheng, Jing;  Yan, Ziqin;  Li, Xinzhi;  Liu, Chen;  Tong, Linjiang   |  收藏  |  浏览/下载：132/0  |  提交时间：2023/12/08 Kinase inhibitor  NIK  NF-KB2  Indoline  COT  Cytotoxicity   Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/02/19 Toxicity identification evaluation for hydraulic fracturing flowback and produced water during shale gas exploitation in China: Evidence from tissue residues and gene expression 期刊论文  OAI收割 WATER RESEARCH, 2023, 卷号: 241, 页码: 12 作者:  Wu, Fan;  Zhou, Zhimin;  Zhang, Shaoqiong;  Cheng, Fei;  Tong, Yujun   |  收藏  |  浏览/下载：80/0  |  提交时间：2024/08/22 Shale gas  Ecological risk from mixtures  Toxicity identification evaluation  Non -target analysis  Organismal uptake  Transcriptomic analysis   Synthesis and Biological Evaluation of Sclareolide-Indole Conjugates and Their Derivatives 期刊论文  OAI收割 MOLECULES, 2023, 卷号: 28, 期号: 4, 页码: 1737 作者:  Cheng, Ying;  Lyu, Xilin;  Liu, Chen;  Wang, Xiancheng;  Cheng, Jing   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/27 sclareolide  indole  polyphenol  acetal  antitumor activity   PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 1, 页码: 157-173 作者:  Sun, Mingming;  Li, Leilei;  Niu, Yujia;  Wang, Yingzhi;  Yan, Qi   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/03/27 Lung cancer  Metabolic reprogramming  Post-translational modification  PRMT6  Pentose phosphate pathway flux  Glycolysis  6-Phospho-gluconate dehydrogenase  a-enolase  ENO1   Text Mining-Based Suspect Screening for Aquatic Risk Assessment in the Big Data Era: Event-Driven Taxonomy Links Chemical Exposures and Hazards 期刊论文  OAI收割 ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2023, 卷号: 10, 期号: 11, 页码: 1004-1010 作者:  Cheng, Fei;  Huang, Jiehui;  Li, Huizhen;  Escher, Beate I.;  Tong, Yujun   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/09/26 BIOMARKER RESPONSES  CONTAMINANTS  TOXICITY  SEDIMENT  BIOAVAILABILITY  MIXTURES  RIVERS