中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [25]
沈阳应用生态研究所 [17]
大连化学物理研究所 [14]
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地理科学与资源研究所 [2]
成都山地灾害与环境研... [1]
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期刊论文 [71]
学位论文 [2]
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2025 [3]
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2023 [2]
2022 [4]
2021 [3]
2019 [4]
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物理化学 [3]
Biochemist... [1]
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浏览/检索结果:
共73条,第1-10条
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Structural Optimization of Next-Generation TRK Inhibitors against Acquired Drug Resistance Mutations for the Treatment of Solid Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 11484-11501
作者:
Xu, Zichao
;
Liu, Yueling
;
Wang, Peng
;
Peng, Xia
;
Cheng, Jiawei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Quantitation of global histone post-translational modifications reveal anti-inflammatory epigenetic mechanisms of liquiritigenin based on the optimized super-SILAC strategy
期刊论文
OAI收割
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2025, 卷号: 13, 页码: 15
作者:
Liu, Ping
;
Zhang, Jun
;
Zhang, Jingdan
;
Yuan, Yucheng
;
Liu, Zhiqing
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/05/27
histone post-translational modifications
super-SILAC
liquiritigenin
inflammation
epigenetics
PPAR
Discovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect
期刊论文
OAI收割
MEDCOMM, 2025, 卷号: 6, 期号: 1, 页码: e70001
作者:
Wang, Xiyuan
;
Zhan, Zhengsheng
;
Wang, Zhen
;
Zhang, Yan
;
Zhao, Kaiyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/06/04
antitumor
immune memory
innate immunity
STING agonist
Metal-organic framework-based SERS chips enable
in situ
and sensitive detection of dissolved hydrogen sulfide in natural water: Towards a bring-back-chip mode for field analysis
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2024, 卷号: 480, 页码: 10
作者:
Si, Meiyu
;
Wang, Yunqing
;
Mei, Rongchao
;
Zhao, Xizhen
;
Yuan, Qi
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/12/06
Hydrogen sulfide
Surface enhanced Raman scattering
Metal-organic framework
in situ sampling
Environmental analysis
Seesaw between the westerlies and Asian monsoon regulates vegetation and climate during the last deglaciation in southern Northeast China
期刊论文
OAI收割
QUATERNARY SCIENCE REVIEWS, 2024, 卷号: 344, 页码: 13
作者:
Wang, Jian
;
Zhang, Guilin
;
Zhang, Wenchao
;
Zhou, Xinying
;
Liu, Junchi
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/06/11
Last deglaciation
Northeast China
Vegetation
East Asian monsoon
Westerly
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 17
作者:
Zhang, Tao
;
Pan, Zilu
;
Gao, Jing
;
Wu, Qingqing
;
Bai, Gang
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/10/21
Efficacy, safety and biomarkers of SG001 for patients with previously treated recurrent or metastatic cervical cancer: an open-label, multicenter, phase Ib trial
期刊论文
OAI收割
CANCER COMMUNICATIONS, 2024
作者:
Zuo, Jing
;
Duan, Wei
;
Zhao, Mingxuan
;
Chen, Zhendong
;
Lin, Jie
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/11/22
Moisture source differences between the 2020 and 1998 super Meiyu-flood events in the Yangtze River Valley
期刊论文
OAI收割
WEATHER AND CLIMATE EXTREMES, 2024, 卷号: 43, 页码: 100644
作者:
Zhang, Chi
;
Tang, Qiuhong
;
Zhao, Yang
;
Chen, Deliang
;
Huang, Jinchuan
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2024/04/08
Meiyu
Precipitation
Moisture source
The Yangtze River valley
WAM2Layers
Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933
作者:
Fang, Feifei
;
Dai, Yang
;
Wang, Hao
;
Ji, Yinchun
;
Liang, Xuewu
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2024/01/26
derivatives
Antitumor drug development
Potential AXL inhibitor
Antitumor activity
Structure-based drug design
Fused-pyrazolone carboxamide
Unprecedented sesterterpenoids, orientanoids A-C: discovery, bioinspired total synthesis and antitumor immunity
期刊论文
OAI收割
CHEMICAL SCIENCE, 2023, 页码: 9
作者:
Zheng, Cheng-Yu
;
Zhao, Jin-Xin
;
Yuan, Chang-Hao
;
Peng, Xia
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2023/12/19