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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-46
作者:
Ling-Chu Chang
;
Hui-Yi Lin
;
Meng-Tung Tsai
;
Ruey-Hwang Chou
;
Fang-Yu Lee
  |  
收藏
  |  
浏览/下载:329/0
  |  
提交时间:2017/07/24
Yc-1
Triple-negative Breast Cancer
Erk
Ezh2
C-cbl
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as novel FLT3/ IRAK4 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 23
作者:
Yuan, Haibin
;
Gao, Yue
;
Wang, Peipei
;
Dong, Xiaowu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
AML
FLT3/IRAK4 inhibitor
Pyrrolo [2,3-d] pyrimidine
Acquired resistance
Adaptive resistance
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
The Overview and Trial Observations of AIMS
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Deng, Yuanyong
;
Wang, Dongguang
;
Hua, Jianwen
;
Xu, Songbo
;
Liang, Ming
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/07/14
Sun: infrared
methods: observational
instrumentation: spectrographs
Ordovician-Devonian granites and Li-Be-bearing pegmatites in the Altyn Tagh Orogen, NW China
期刊论文
OAI收割
GEOLOGICAL SOCIETY OF AMERICA BULLETIN, 2025, 页码: 21
作者:
Jing, Yan
;
Zhang, Chuan-lin
;
Wang, Chen
;
Ge, Wen-chun
;
Song, Zhi-hao
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/07/11
Spectroscopic characterization of buffer-gas-cooled lead monofluoride molecules in the
B
2 Σ + ( v '=0) ←
X
1 2Π1/2(v=0) transition
期刊论文
OAI收割
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2025, 卷号: 329, 页码: 125508
作者:
Wang, Zesen
;
Pang, Renjun
;
Ma, Jie
;
Lin, Qinning
;
Hou, Shunyong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/02/27
Lead monofluoride (PbF) molecule
buffer-gas cooling (BGC)
electron Electric Dipole Moment ( e EDM)
Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:
Jin, Yuheng
;
Qi, Xuxin
;
Yu, Xiaoli
;
Cheng, Xirui
;
Chen, Boya
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/06/23
HDAC7
PROTAC
Selectivity
Hematologic malignancies
Non-enzymatic function
Advance on the effects of algal carotenoids on inflammatory signaling pathways
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 13
作者:
Wang, Yudi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/01/10
Algal carotenoids
Inflammatory signaling pathways
Targeting effect
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/04/01