中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [51]
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A holistic strategy for the in-depth discrimination and authentication of 16 citrus herbs and associated commercial products based on machine learning techniques and non-targeted metabolomics
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2025, 卷号: 1745, 页码: 12
作者:
Huang, Yu-shi
;
An, Ya-ling
;
Zheng, Yue-yuan
;
Zhao, Wen-jie
;
Song, Chun-qian
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
Citrus herbs
Discrimination
LC-MS
Machine learning
Differential markers
Current landscape of metal-organic framework-mediated nucleic acid delivery and therapeutics
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 卷号: 672, 页码: 21
作者:
Feng, Shiwei
;
Li, Yan
;
Tan, Zheng
;
Shen, Shiyang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
Metal-organic frameworks
Nucleic acids
Nanocarrier
Drug delivery
Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel
Hs
ClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:
Sun, Mingyang
;
Chen, Beijing
;
Teng, Dan
;
Zhao, Hongshen
;
Liao, Yilie
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma
期刊论文
OAI收割
CELL DISCOVERY, 2025, 卷号: 11, 期号: 1, 页码: 24
作者:
Cheng, Yifei
;
Chen, Xiaofang
;
Feng, Li
;
Yang, Zhicheng
;
Xiao, Liyun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
The Significant Therapeutic Effects of Chinese Scorpion: Modern Scientific Exploration of Ion Channels
期刊论文
OAI收割
PHARMACEUTICALS, 2024, 卷号: 17, 期号: 12, 页码: 18
作者:
Zheng, Yueyuan
;
Wen, Qiuyi
;
Huang, Yushi
;
Guo, Dean
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/02/28
Buthus martensii
Karsch
ion channel
chemical components
pharmacological effects
Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Chen, Beijing
;
Sun, Mingyang
;
Zhang, Chun
;
Huang, Qi
;
Teng, Dan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/25
Solvent-Controlled Divergent Cyclization of 3-Ylideneoxindoles with Ethyl 2-Diazoacetate: Access to Spirocyclopropyl and Spiropyrazolines Oxindoles
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2024, 页码: 7
作者:
Xie, Ding-Xiong
;
Huang, Yue-Mei
;
Lin, Xiao-Ming
;
Kang, Zheng-Hui
;
Ni, Chen-Chen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/11
Spirocyclopropyl oxindole
Spiropyrazoline oxindole
Catalyst-free
Solvent-controlled
3-Ylideneoxindole
Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
期刊论文
OAI收割
CELL METABOLISM, 2024, 卷号: 36, 期号: 10, 页码: 25
作者:
Zhou, Bing
;
Luo, Yunchen
;
Bi, Hanqi
;
Zhang, Ni
;
Ma, Mingyue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/11/26