机构

• 上海药物研究所 [19]
• 新疆理化技术研究所 [2]
• 地球化学研究所 [1]

采集方式

• OAI收割 [22]

内容类型

• 期刊论文 [22]

发表日期

• 2024 [3]
• 2023 [3]
• 2022 [1]
• 2021 [3]
• 2020 [2]
• 2019 [4]
• 更多

学科主题

筛选

浏览/检索结果: 共22条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia 期刊论文  OAI收割 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 242, 页码: 13 作者:  Cheng, Jiaxin;  Wu, Chunhui;  Wang, Yu;  Wang, Zhen;  He, Yang   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/09/24 TPN672MA  5-HT 1A receptor agonist  D 2 /D 3 receptor partial agonist  5-HT 2A receptor antagonist  Antidepressant-like  Mechanism   Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4855-4869 作者:  Gu, Chenming;  Liu, Jiayuan;  Qian, Fei;  Yu, Wenchao;  Huang, Doudou   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/05/07 Cannabidiol exhibits anxiolytic-like effects and antipsychotic-like effects in mice models 期刊论文  OAI收割 NEUROSCIENCE LETTERS, 2024, 卷号: 826, 页码: 8 作者:  Shu, Guangzhao;  He, Yang;  Suo, Jin;  Wu, Chunhui   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/06/27 Cannabidiol  Stress-induced hyperthermia  Phencyclidine-induced negative symptoms of  schizophrenia model  5-HT 1A receptor   Acute Hemodynamic Study Of Oral TPN171H In Patients With Pulmonary Arterial Hypertension: A Multicenter, Randomized, Controlled, Phase 2 Clinical Trial 期刊论文  OAI收割 CIRCULATION, 2023, 卷号: 148, 期号: 25, 页码: E300-E300 作者:  Zhou, Yu-Ping;  Ma, Wei;  Cao, Yunshan;  Li, Jiang;  Huang, Wei   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/11/05 Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221 作者:  He Yifei;  Liu Yin;  Yu Jinghua;  Cheng Huan;  Odilov Abdullajon   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/05/22 TPN171  14CTPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   基于UMAP与HDBSCAN的北京市极端暴雨时空动态分布规律研究 期刊论文  OAI收割 北京师范大学学报(自然科学版), 2023, 卷号: 59, 期号: 2, 页码: 269-279 作者:  徐淑高;  王纤阳;  蒋卫威;  鱼京善;  刘源   |  收藏  |  浏览/下载：2/0  |  提交时间：2023/10/23 TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats 期刊论文  OAI收割 VASCULAR PHARMACOLOGY, 2022, 卷号: 145, 页码: 11 作者:  Zhao, Congke;  Hu, Liqing;  He, Xiangrong;  Li, Lijun;  Yin, Minghui   |  收藏  |  浏览/下载：52/0  |  提交时间：2022/08/16 Pulmonary hypertension  Hypoxia  Monocrotaline  Anti-inflammatory effects  NLRP3 inflammasome  Pulmonary artery endothelial cells   TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia 期刊论文  OAI收割 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 378, 期号: 1, 页码: 20-30 作者:  Wang, Yu;  He, Yang;  Yang, Feipu;  Abame, Melkamu Alemu;  Wu, Chunhui   |  收藏  |  浏览/下载：46/0  |  提交时间：2021/11/04 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文  OAI收割 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang   |  收藏  |  浏览/下载：93/0  |  提交时间：2021/08/17 A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects 期刊论文  OAI收割 DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959 作者:  Qian, Hongjie;  Chen, Qian;  Lang, Liyu;  Zou, Yang;  Pu, Huahua   |  收藏  |  浏览/下载：27/0  |  提交时间：2021/08/17 TPN171H  PDE5 inhibitor  safety  pharmacokinetics  food effect  healthy subjects