机构

• 合肥物质科学研究院 [47]
• 上海药物研究所 [1]
• 大连化学物理研究所 [1]

采集方式

• OAI收割 [49]

内容类型

• 期刊论文 [49]

发表日期

• 2024 [2]
• 2022 [3]
• 2021 [3]
• 2020 [3]
• 2019 [3]
• 2018 [8]
• 更多

学科主题

筛选

浏览/检索结果: 共49条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of Pyrazolo[1,5-a]pyridine Derivatives as Potent and Selective PI3Kγ/δ Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024 作者:  Wang, Chun;  Zou, Fengming;  Qi, Ziping;  Liu, Qingwang;  Shen, Lijuan   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/11/20 A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension 期刊论文  OAI收割 EXPERIMENTAL CELL RESEARCH, 2024, 卷号: 441 作者:  Huang, Wen;  Zhou, Hong;  He, Yiting;  Wang, Aoli;  Wang, Beilei   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/11/22 WQ-C-401  Pulmonary arterial hypertension  Pulmonary vascular remodeling  Platelet-derived growth factor receptor  Smooth muscle cells   Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243 作者:  Liang, Xiaofei;  Wang, Chun;  Wang, Beilei;  Liu, Juan;  Qi, Shuang   |  收藏  |  浏览/下载：54/0  |  提交时间：2022/12/23 CSF1R inhibitor  Kinase inhibitor  Macrophage polarization   A spiropyran with low pK(a) for tracking DNA G-quadruplexes and revealing the dissipation of Delta Psi m with senescence using an in-situ switching strategy 期刊论文  OAI收割 SENSORS AND ACTUATORS B-CHEMICAL, 2022, 卷号: 359 作者:  Tian, Xinrong;  Li, Jin;  Zhang, Yanhui;  Gao, Ying;  Afzal, Muhammad Wasim   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/12/22 Fluorescent probes  G-quadruplexes  Membrane potential of mitochondria  Senescence  Senescent cells   Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2 期刊论文  OAI收割 LEUKEMIA, 2022 作者:  Yang, Jing;  Weisberg, Ellen L.;  Qi, Shuang;  Ni, Wei;  Mei, Husheng   |  收藏  |  浏览/下载：88/0  |  提交时间：2022/02/14 Targeting chaperon protein HSP70 as a novel therapeutic strategy for FLT3-ITD-positive acute myeloid leukemia 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6 作者:  Hu, Chen;  Zou, Fengming;  Wang, Aoli;  Miao, Weili;  Liang, Qianmao   |  收藏  |  浏览/下载：57/0  |  提交时间：2021/11/01 Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML) 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897 作者:  Lu, Tingting;  Cao, Jiangyan;  Zou, Fengming;  Li, Xixiang;  Wang, Aoli   |  收藏  |  浏览/下载：59/0  |  提交时间：2021/04/26 BCR-ABL  ABL mutants  Chronic myeloid leukemia  Kinase inhibitor  Imatinib resistance   Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia 期刊论文  OAI收割 HAEMATOLOGICA, 2021, 卷号: 106 作者:  Wang, Aoli;  Hu, Chen;  Chen, Cheng;  Liang, Xiaofei;  Wang, Beilei   |  收藏  |  浏览/下载：72/0  |  提交时间：2021/04/26 Discovery of a highly potent and selective Bruton's tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5 作者:  Liu, Juan;  Liang, Qianmao;  Wang, Aoli;  Zou, Fengming;  Qi, Ziping   |  收藏  |  浏览/下载：48/0  |  提交时间：2020/11/30 Network-based analysis with primary cells reveals drug response landscape of acute myeloid leukemia 期刊论文  OAI收割 EXPERIMENTAL CELL RESEARCH, 2020, 卷号: 393 作者:  Chen, Cheng;  Wang, Li;  Li, Lili;  Wang, Aoli;  Huang, Tao   |  收藏  |  浏览/下载：55/0  |  提交时间：2020/11/26 Acute myeloid leukemia (AML)  Drug response  Gene mutations