中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
合肥物质科学研究院 [2]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2023 [1]
2022 [1]
2021 [1]
2020 [1]
2018 [3]
学科主题
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Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:
Liang, Xiaofei
;
Wang, Chun
;
Wang, Beilei
;
Liu, Juan
;
Qi, Shuang
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/12/23
CSF1R inhibitor
Kinase inhibitor
Macrophage polarization
Magnetism-mediated targeting hyperthermia-immunotherapy in "cold" tumor with CSF1R inhibitor
期刊论文
OAI收割
THERANOSTICS, 2021, 卷号: 11, 期号: 14, 页码: 6860-6872
作者:
Fang, Yuefei
;
He, Yang
;
Wu, Canhao
;
Zhang, Meng
;
Gu, Zeyun
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
magnetic hyperthermia
CSF1R inhibitor
tumor microenvironment
tumor-associated macrophage
immune memory
targeted delivery
magnetic liposomes
Discovery of a highly selective VEGFR2 kinase inhibitor CHMFL-VEGFR2-002 as a novel anti-angiogenesis agent
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10
作者:
Jiang, Zongru
;
Wang, Li
;
Liu, Xuesong
;
Chen, Cheng
;
Wang, Beilei
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/11/26
Cancer
VEGFR2 kinase
Kinase inhibitor
Angiogenesis
Inhibitor selectivity
Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1768-1776
作者:
Liu, Ying-Qiang
;
Wang, Ya-Nan
;
Lu, Xiao-Yun
;
Tong, Lin-Jiang
;
Li, Yan
  |  
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2019/01/08
CSF-1R
small-molecule inhibitor
macrophage
myeloid leukemia
Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 6, 页码: 2353-2371
作者:
Xun, Qiuju
;
Zhang, Zhang
;
Luo, Jinfeng
;
Tong, Linjiang
;
Huang, Minhao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
identificationofcompoundd2923asanovelantitumoragenttargetingcsf1r
期刊论文
OAI收割
actapharmacologicasinica, 2018, 卷号: 039, 期号: 011, 页码: 1768
作者:
Liu Yingqiang
;
Wang Yanan
;
Lu Xiaoyun
;
Tong Linjiang
;
Li Yan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
肿瘤组织
代理人
apoptosis
生长抑制率
复合
指向
鉴定
巨噬细胞