机构

• 上海药物研究所 [12]
• 武汉物理与数学研究所 [1]
• 上海营养与健康研究所 [1]
• 烟台海岸带研究所 [1]

采集方式

• OAI收割 [15]

内容类型

• 期刊论文 [15]

发表日期

• 2025 [1]
• 2024 [1]
• 2023 [2]
• 2017 [3]
• 2016 [4]
• 2015 [2]
• 更多

学科主题

• Biochemist... [1]
• Biophysics [1]

筛选

浏览/检索结果: 共15条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21 作者:  Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/12/25 Synthetic lethal  MSI tumors  WRN inhibitors  Triazolo-pyrimidine derivatives   FuncPhos-STR: An integrated deep neural network for functional phosphosite prediction based on AlphaFold protein structure and dynamics 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 266, 页码: 11 作者:  Zhang, Guangyu;  Zhang, Cai;  Cai, Mingyue;  Luo, Cheng;  Zhu, Fei   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/06/27 Functional phosphosite  Deep learning  AlphaFold protein structure  Dynamics  Protein protein interaction   Goliath induces inflammation in obese mice by linking fatty acid β-oxidation to glycolysis 期刊论文  OAI收割 EMBO REPORTS, 2023, 卷号: 24, 期号: 4 作者:  Hao, Shumeng;  Zhang, Sulin;  Ye, Jialin;  Chen, Lifan;  Wang, Yan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/27 FAO  glycolysis  Goliath  inflammation  obesity   Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214 作者:  Zhou, Zehui   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/03/27 Analysis and prediction of drug-drug interaction by minimum redundancy maximum relevance and incremental feature selection 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2017, 卷号: 35, 期号: 2, 页码: 312-329 作者:  Liu, Lili;  Chen, Lei;  Zhang, Yu-Hang;  Wei, Lai;  Cheng, Shiwen   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Drug-drug interaction  drug-target interaction  chemical interaction  protein interaction  minimum redundancy maximum relevance  incremental feature selection   Predicting Hepatotoxicity of Drug Metabolites Via an Ensemble Approach Based on Support Vector Machine 期刊论文  OAI收割 COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2017, 卷号: 20, 期号: 10, 页码: 839-849 作者:  Lu, Yin;  Liu, Lili;  Lu, Dong;  Cai, Yudong;  Zheng, Mingyue   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 DILI  hepatotoxicity  QSAR  drug metabolites  mRMR  SVM   Analysis and prediction of drug-drug interaction by minimum redundancy maximum relevance and incremental feature selection 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2017, 卷号: 35, 期号: 2, 页码: 312-329 作者:  Liu, Lili;  Chen, Lei;  Wei, Lai;  Cheng, Shiwen;  Zhang, Yu-Hang   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/12/09 Drug-drug interaction  drug-target interaction  chemical interaction  protein interaction  minimum redundancy maximum relevance  incremental feature selection   Identification of compound-protein interactions through the analysis of gene ontology, KEGG enrichment for proteins and molecular fragments of compounds 期刊论文  OAI收割 MOLECULAR GENETICS AND GENOMICS, 2016, 卷号: 291, 期号: 6, 页码: 2065-2079 作者:  Chen, Lei;  Zhang, Yu-Hang;  Zheng, Mingyue;  Huang, Tao;  Cai, Yu-Dong   |  收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 Compound-protein interaction  Gene ontology enrichment  KEGG enrichment  Minimum redundancy maximum relevance  Incremental feature selection   Identification of novel candidate drivers connecting different dysfunctional levels for lung adenocarcinoma using protein-protein interactions and a shortest path approach 期刊论文  OAI收割 SCIENTIFIC REPORTS, 2016, 卷号: 6 作者:  Chen, Lei;  Huang, Tao;  Zhang, Yu-Hang;  Jiang, Yang;  Zheng, Mingyue   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Identification of new candidate drugs for lung cancer using chemical-chemical interactions, chemical-protein interactions and a K-means clustering algorithm 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2016, 卷号: 34, 期号: 4, 页码: 906-917 作者:  Lu, Jing;  Chen, Lei;  Yin, Jun;  Huang, Tao   |  收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08 chemical-protein interaction  K-means clustering algorithm  lung cancer  chemical-chemical interaction