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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [85]
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One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18
作者:
Li, Huaxuan
;
Yang, Hong
;
Liu, Li
;
Zheng, Jiahong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/12/11
Protein arginine methyltransferase 5
Nucleoside derivatives
Piperazine
Metabolic stability
Symmetric dimethylarginines
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:
Chen, Jiexuan
;
Wu, Mingfei
;
Mo, Jun
;
Hong, Ju
;
Wang, Wei
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/04/01
GRB 240529A: A Tale of Two Shocks
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 976, 期号: 2
作者:
Sun, Tian-Rui
;
Geng, Jin-Jun
;
Yan, Jing-Zhi
;
Hu, You-Dong
;
Wu, Xue-Feng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/02
Discovery of CZL-046 with an (
S
)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 20, 页码: 18606-18628
作者:
Chen, Zonglong
;
Yang, Hong
;
Zhang, Yan
;
Lyu, Xiaodong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/11/05
Efficacy and safety of
Bacteroides fragilis
BF839 for pediatric autism spectrum disorder: a randomized clinical trial
期刊论文
OAI收割
FRONTIERS IN NUTRITION, 2024, 卷号: 11, 页码: 12
作者:
Lin, Chu-hui
;
Zeng, Ting
;
Lu, Cui-wei
;
Li, De-yang
;
Liu, Yi-ying
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/10/14
autism spectrum disorder in children
probiotics
Bacteroides fragilis BF839
abnormal behavior
gastrointestinal symptoms
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/09/10
FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15
作者:
Wen, Ying-quan
;
Zou, Zi-yuan
;
Zhao, Guan-guan
;
Zhang, Meng-jiao
;
Zhang, Yong-xin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/08/22
MASLD/MASH
FXR
transcriptome
gut-liver axis
agonist
Chemical constituents from the twigs with leaves of
Tetradium trichotomum
期刊论文
OAI收割
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2024, 页码: 7
作者:
Chen, Hong-Lian
;
Yao, Jia-Ying
;
Gao, Ming-Hui
;
Tan, Jun-Jie
;
Qu, Shi-Jin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/22
Rutaceae
Tetradium trichotomum
limonoids
amide alkaloids
immunosuppressant
lymphocytes
Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer
期刊论文
OAI收割
CANCER RESEARCH, 2024, 卷号: 84, 期号: 12, 页码: 1963-1977
作者:
Gai, Xiameng
;
Liu, Yingluo
;
Lan, Xiaojing
;
Chen, Luoyi
;
Yuan, Tao
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/08/20
Consistent time allocation fraction to vegetation green-up versus senescence across northern ecosystems despite recent climate change
期刊论文
OAI收割
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 23, 页码: 11
作者:
Meng, Fandong
;
Felton, Andrew J.
;
Mao, Jiafu
;
Cong, Nan
;
Smith, William K.
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/10/08