机构

• 上海药物研究所 [20]
• 西北高原生物研究所 [10]
• 昆明植物研究所 [7]
• 昆明动物研究所 [7]
• 上海有机化学研究所 [4]
• 大连化学物理研究所 [3]
• 更多

采集方式

• OAI收割 [61]
• iSwitch采集 [2]

内容类型

• 期刊论文 [63]

发表日期

• 2023 [2]
• 2022 [2]
• 2021 [3]
• 2019 [3]
• 2018 [2]
• 2017 [2]
• 更多

学科主题

• 生命有机化学 [4]
• Pharmacolo... [3]
• Chemistry,... [2]
• Chemistry,... [2]
• Plant Scie... [2]
• Biochemica... [1]
• 更多

筛选

浏览/检索结果: 共63条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Synthesis and evaluation of NHC derivatives and 4′-fluorouridine prodrugs 期刊论文  OAI收割 ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 13, 页码: 2754-2767 作者:  Xiang, Li;  Hu, Tianwen;  Xue, Haitao;  Pan, Wenfang;  Xie, Yuanchao   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27 Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20 作者:  Chen, Yuting;  Shi, Qiongyu;  Yang, Hong;  Li, Jiayi;  Zhou, Kaixin   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 Epigenetic  PRMT5 inhibitor  Nucleoside derivatives  Structure-activity Relationship Prodrug   Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555 作者:  Li, Ennian;  Wang, Kai;  Zhang, Bei;  Guo, Siqi;  Xiao, Senhao   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 DNMT1 inhibitor  A549 cell lines  HCT116 cell lines  antitumor activity  pharmacokinetic   Development and validation of an LC-MS/MS method for simultaneous determination of remdesivir and its hydrolyzed metabolite and nucleoside, and its application in a pharmacokinetic study of normal and diabetic nephropathy mice 期刊论文  OAI收割 BIOMEDICAL CHROMATOGRAPHY, 2022, 页码: 10 作者:  Yuan, Meng;  Hu, Wenjuan;  Feng, Yingying;  Tong, Yue;  Wang, Xin   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/06/15 diabetic nephropathy  LC-MS  MS  nucleoside  pharmacokinetics  remdesivir   Chemical Synthesis of the Nucleoside Antibiotic Capuramycin 期刊论文  OAI收割 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 2021, 期号: 26, 页码: 3681-3689 作者:  Xiao,Guozhi;  He,Haiqing   |  收藏  |  浏览/下载：19/0  |  提交时间：2022/04/02 Capuramycin  Chemical synthesis  Glycosyl ortho-(1-phenylvinyl)benzoates  One-pot glycosylation  Tuberculosis  DRUG-RESISTANT TUBERCULOSIS  GLUTAMIC-ACID-DERIVATIVES  MULTIDRUG-RESISTANT  PROTECTING GROUPS  IN-VITRO  GLYCOSYLATION  INHIBITORS  ALCOHOLS  ANALOGS  OXIDATION   One new nucleoside and three furanpentanone derivatives from the aerial part of Rubia cordifolia L 期刊论文  OAI收割 PHYTOCHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 125-128 作者:  He,Dong-Bing;  Bai,Xue;  Ma,Yu-Han;  Qin,Hai-Jun;  Wu,Yi-Bing   |  收藏  |  浏览/下载：45/0  |  提交时间：2022/04/02 Rubia cordifolia  Secondary metabolites  NO production inhibition  A-C  ROOTS  ANTHRAQUINONES  CYTOTOXICITY  CONSTITUENTS   Potency and pharmacokinetics of GS-441524 derivatives against SARS-CoV-2 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 46, 期号: 9, 页码: 1-12 作者:  Wei, DB (Wei, Daibao);  Hu, TW (Hu, Tianwen);  Zhang, YM (Zhang, Yumin);  Zheng, W (Zheng, Wei);  Xue, HT (Xue, Haitao)   |  收藏  |  浏览/下载：74/0  |  提交时间：2021/10/14 Covid-19  SARS-CoV-2  GS-441524  Antiviral  Nucleoside  Prodrug  Isobutyrate   Discovery of pyrimidine nucleoside dual prodrugs and pyrazine nucleosides as novel anti-HCV agents 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 5, 页码: 748-759 作者:  Guo, Shuang;  Xu, Mingshuo   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 Nucleoside  Double prodrug  Phosphoramidate  Anti-HCV  Pyrazine   Stereoselective N-glycosylation with N-4-acyl cytosines and efficient synthesis of gemcitabine 期刊论文  OAI收割 TETRAHEDRON, 2019, 卷号: 75, 期号: 9, 页码: 1203-1213 作者:  Liu, Tongchao;  Tang, Jiadeng;  Liang, Jianpeng;  Chen, Yabin   |  收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01 Stereoselective  N-glycosylation  N-4-acyl cytosine  Nucleoside  Gemcitabine   Nucleoside and N-acetyldopamine derivatives from the insect Aspongopus chinensis 期刊论文  OAI收割 2019 -   |  收藏  |  浏览/下载：5/0  |  提交时间：2020/04/02