中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共201条,第1-10条 帮助

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Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:  
Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong
  |  收藏  |  浏览/下载:0/0  |  提交时间:2025/06/23
Structural optimization and discovery of high effective isopropanolamine-based TPS1 inhibitors as promising broad-spectrum fungicide candidates 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 290, 页码: 17
作者:  
Jiang, Zhiyang;  Wang, Na;  Chen, Jinxiu;  Xu, Huan;  Zhu, Wenya
  |  收藏  |  浏览/下载:0/0  |  提交时间:2025/05/27
Development of RelB-targeting small-molecule inhibitors of non-canonical NF-kB signaling with antitumor efficacy 期刊论文  OAI收割
MOLECULAR THERAPY, 2025, 卷号: 33, 期号: 4, 页码: 1519-1534
作者:  
Li, Cuifeng;  Wei, Shuqi;  Sun, Donglin;  Yang, Zhuo;  Wang, Qi
  |  收藏  |  浏览/下载:0/0  |  提交时间:2025/05/27
REG3A secreted by peritumoral acinar cells enhances pancreatic ductal adenocarcinoma progression via activation of EGFR signaling 期刊论文  OAI收割
CELL COMMUNICATION AND SIGNALING, 2025, 卷号: 23, 期号: 1, 页码: 19
作者:  
Ren, Xiaojing;  Teng, Yunfei;  Xie, Kunxin;  He, Xiao;  Chen, Gang
  |  收藏  |  浏览/下载:18/0  |  提交时间:2025/04/01
Novel conjugated 5-alkenyl rhodanine tethered 1,4-benzodioxane derivatives as dual-chitinases inhibitors to hinder the growth of Asian corn borer 期刊论文  OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2025, 页码: 13
作者:  
Chen, Jinxiu;  Shi, Dongmei;  Jiang, Zhiyang;  Zou, Renxuan;  Zhang, Jingyu
  |  收藏  |  浏览/下载:7/0  |  提交时间:2025/04/01
Identification of the VP37 pocket of monkeypox virus as a promising target for pan-orthopoxvirus inhibitors through virtual screening and antiviral assays 期刊论文  OAI收割
EMERGING MICROBES & INFECTIONS, 2024, 卷号: 13, 期号: 1, 页码: 4
作者:  
Huo, Shuting;  Wu, Leyun;  Huang, Baoying;  Liu, Nan;  Sun, Jiewei
  |  收藏  |  浏览/下载:19/0  |  提交时间:2024/08/22
F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13
作者:  
Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu
  |  收藏  |  浏览/下载:13/0  |  提交时间:2025/02/28
Development of an FAP-Targeted PET Probe Based on a Novel Quinolinium Molecular Scaffold 期刊论文  OAI收割
BIOCONJUGATE CHEMISTRY, 2024, 页码: 9
作者:  
Li, Lei;  Cao, Rui;  Chen, Kaixin;  Qu, Chunrong
  |  收藏  |  浏览/下载:13/0  |  提交时间:2024/08/22
Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma 期刊论文  OAI收割
HAEMATOLOGICA, 2024, 卷号: 109, 期号: 4, 页码: 1206-1219
作者:  
Chen, Gege;  Gao, Xuejie;  Jia, Xinyan;  Wang, Yingcong;  Xu, Li
  |  收藏  |  浏览/下载:32/0  |  提交时间:2024/05/07
A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory 期刊论文  OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:  
Zhang, Hui;  Hu, Ke;  Lu, Yumeng;  Xu, Zhijian;  Chen, Gege
  |  收藏  |  浏览/下载:38/0  |  提交时间:2024/03/25