机构

• 上海药物研究所 [13]
• 昆明植物研究所 [5]
• 化学研究所 [3]
• 过程工程研究所 [3]
• 心理研究所 [2]
• 海洋研究所 [2]
• 更多

采集方式

• OAI收割 [44]
• iSwitch采集 [1]

内容类型

• 期刊论文 [44]
• 会议论文 [1]

发表日期

• 2025 [2]
• 2024 [7]
• 2023 [1]
• 2022 [3]
• 2021 [8]
• 2020 [2]
• 更多

学科主题

• Pharmacolo... [2]
• Agricultur... [1]
• Chemistry [1]
• Chemistry,... [1]
• Ecology [1]
• Environmen... [1]
• 更多

筛选

浏览/检索结果: 共45条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 PEGylation of Dipeptide Linker Improves Therapeutic Index and Pharmacokinetics of Antibody-Drug Conjugates 期刊论文  OAI收割 BIOCONJUGATE CHEMISTRY, 2025, 页码: 11 作者:  Long, Jing;  Shao, Ting;  Wang, Yongmei;  Chen, Tianzhi;  Chen, Yuning   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/04/01 Simultaneous Quantification of Total Antibody and Conjugated Payload for DS001 in Rat Serum Using a Hybrid Immuno-Capture LC-MS/MS 期刊论文  OAI收割 AAPS JOURNAL, 2025, 卷号: 27, 期号: 1, 页码: 13 作者:  Yu, Xiong;  Li, Weiqiang;  Huang, Wensi;  Xiao, Bo;  Long, Jing   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/04/01 ADC  LC-MS/MS  payload  simultaneous quantification  total antibody   Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16 作者:  Nie, Hui-Jun;  Li, Ben-Fu;  Sun, Jingya;  Yuan, Yali;  Zhang, Zhi-Gao   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/11/26 Triple-negative breast cancer  Targeting transcription regulation  Orally bioavailable degrader  PROTAC  Cyclin-dependent Kinase 9   Discovery of Orally Bioavailable and Potent CDK9 Inhibitors for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 12, 页码: 10035-10056 作者:  Wang, Wen-Jing;  Gao, Lixin;  Wang, Simei;  Huang, Wensi;  Meng, Xin-Yu   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/08/20 Cross-ancestry genome-wide association studies of brain imaging phenotypes 期刊论文  OAI收割 NATURE GENETICS, 2024, 页码: 31 作者:  Fu, Jilian;  Zhang, Quan;  Wang, Jianhua;  Wang, Meiyun;  Zhang, Bing   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/06/29 Species identification and biomass assessment of Gnathanodon speciosus based on environmental DNA technology 期刊论文  OAI收割 ECOLOGICAL INDICATORS, 2024, 卷号: 160, 页码: 9 作者:  Zhang, Jing;  Chen, Xiaofei;  Zhou, Qingjie;  Diao, Caoyun;  Jia, Hui   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/06/04 Environmental DNA  Aquarium experiment  Biomass assessment  Gnathanodon speciosus   A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay 期刊论文  OAI收割 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11 作者:  Huang, Wen-si;  Li, Wei-qiang;  Yu, Xiong;  Xue, Ming-zhen;  Yuan, Ya-li   |  收藏  |  浏览/下载：39/0  |  提交时间：2024/04/09 Anti -gastric cancer monoclonal antibody  Ramucirumab  LC -MS/MS  Method validation  Surrogate peptide   Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11 作者:  Wang, Weiqiang;  Chen, Chong;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：36/0  |  提交时间：2024/01/16 LN005  Metabolism  Peptide -drug conjugates  UHPLC-HRMS  Doxorubicin   Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS 期刊论文  OAI收割 XENOBIOTICA, 2024, 页码: 9 作者:  Yuan, Yali;  Wang, Weiqiang;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/02/19 peptide-drug conjugate  PDC  LN005  metabolite identification  liver S9s   Development and validation of a LC-MS/MS method for quantitation of recombinant human growth hormone in rat plasma and application to a pharmacokinetic study 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 224, 页码: 9 作者:  Huang, Wen-si;  Yu, Jing-hua;  Diao, Xing-xing   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/04/10 Recombinant human growth hormone (rhGH)  Somatotropin  Method validation  LC-MS  MS  Pharmacokinetics