中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
昆明植物研究所 [5]
植物研究所 [4]
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期刊论文 [40]
会议论文 [1]
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2024 [3]
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浏览/检索结果:
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A robust and validated LC-MS/MS method for the quantification of ramucirumab in rat and human serum using direct enzymatic digestion without immunoassay
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 11
作者:
Huang, Wen-si
;
Li, Wei-qiang
;
Yu, Xiong
;
Xue, Ming-zhen
;
Yuan, Ya-li
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/04/09
Anti -gastric cancer monoclonal antibody
Ramucirumab
LC -MS/MS
Method validation
Surrogate peptide
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:
Wang, Weiqiang
;
Chen, Chong
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/01/16
LN005
Metabolism
Peptide -drug conjugates
UHPLC-HRMS
Doxorubicin
Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS
期刊论文
OAI收割
XENOBIOTICA, 2024, 页码: 9
作者:
Yuan, Yali
;
Wang, Weiqiang
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/19
peptide-drug conjugate
PDC
LN005
metabolite identification
liver S9s
Development and validation of a LC-MS/MS method for quantitation of recombinant human growth hormone in rat plasma and application to a pharmacokinetic study
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 224, 页码: 9
作者:
Huang, Wen-si
;
Yu, Jing-hua
;
Diao, Xing-xing
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
Recombinant human growth hormone (rhGH)
Somatotropin
Method validation
LC-MS
MS
Pharmacokinetics
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1 beta and IL-6
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4180-4192
作者:
Liao, Liping
;
Dang, Wenzhen
;
Lin, Tingting
;
Yu, Jinghua
;
Liu, Tonghai
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Glycolysis
Phosphoglycerate kinase 1
Macrophages
NRF2
Inflammation
Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:
He, Yi-fei
;
Liu, Yin
;
Yu, Jing-hua
;
Cheng, Huan
;
Odilov, Abdullajon
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/08/16
TPN171
[C-14]TPN171
PDE5 inhibitor
pulmonary arterial hypertension
healthy volunteers
pharmacokinetics
metabolite identification
mass balance
Two Novel Rare Earth Coordination Polymers Derived from Zwitterionic 1,3-Bis(1-carboxylatoethyl)imidazolium Bromide: Structures and Magnetic Properties
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2022, 卷号: 1250, 页码: 8
作者:
Liu, Mengchen
;
Yin, Qianqian
;
Zhong, Shengnan
;
Sun, Huimin
;
Wang, Yibo
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/06/15
Rare earth
Coordination polymer
Zwitterionic ligand
X-ray diffraction
Magnetic Property
Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2021, 卷号: 12
作者:
Chen, Ming
;
Chen, Runzhe
;
Jin, Ying
;
Li, Jun
;
Hu, Xin
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2022/01/10
Solvothermal Synthesis and Conformation Probe of Novel Europium Complex of Bronsted Acidic Ionic Liquid: 1,3-Bis(1-carboxylatoethyl)imidazolium Bromide
期刊论文
OAI收割
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 2021, 页码: 10
作者:
Sun, Huimin
;
Liu, Mengchen
;
Fu, Xiaofang
;
Xin, Tingting
;
Wang, Yibo
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/08/31
Metal organic frameworks
Europium complex
Solvothermal synthesis
Ionic liquid
Luminescence probe
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
期刊论文
OAI收割
AUTOPHAGY, 2021, 卷号: 17
作者:
Klionsky, Daniel J.
;
Abdel-Aziz, Amal Kamal
;
Abdelfatah, Sara
;
Abdellatif, Mahmoud
;
Abdoli, Asghar
  |  
收藏
  |  
浏览/下载:282/0
  |  
提交时间:2021/05/31
Autophagosome
cancer
flux
LC3
lysosome
macroautophagy
neurodegeneration
phagophore
stress
vacuole