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From Hit to Lead: Discovery of Novel Selective RIPK1 Inhibitor with Pyridoimidazole Scaffold for the Treatment of Autoimmune Diseases through Phenotypic Screening and Structural Optimization
期刊论文
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JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 69, 期号: 3, 页码: 3252-3288
作者:
Wan, Jihong
;
Xiong, Xiao-Yu
;
Geng, Zixiang
;
Yuan, Benjun
;
Ma, Youzhen
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Targeting intrinsic and CAF-mediated signaling by PI3Kα inhibitor CYH33 attenuated metastasis in lung squamous cell carcinoma
期刊论文
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ACTA PHARMACOLOGICA SINICA, 2026, 页码: 14
作者:
Ma, Xiao-yu
;
Deng, Jie-ting
;
Cao, Zhe-rui
;
Xu, Lan
;
Ding, Jian
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Characteristics and controlling factors of stable isotopes in precipitation based on 9-year monitoring data in the monsoon transition zone of the Tibetan Plateau
期刊论文
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AGRICULTURAL AND FOREST METEOROLOGY, 2026, 卷号: 376, 页码: 15
作者:
Shao-yong, Wang
;
Qiao-li, Wang
;
Shi-chang, Kang
;
Yong-jian, Ding
;
Yu-ang, Xue
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O
-GlcNAcylation of AMFR stabilizes TSPAN4 to regulate migrasome formation for viral release
期刊论文
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NATURE COMMUNICATIONS, 2026, 卷号: 17, 期号: 1, 页码: 19
作者:
Yu, Linghui
;
Li, Jiajia
;
Han, Yiyang
;
Yang, Xiao
;
Fu, Yu
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BMAL1/PGC1a4-FNDC5/irisin axis impacts distinct outcomes of time-of-day resistance exercise
期刊论文
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JOURNAL OF SPORT AND HEALTH SCIENCE, 2025, 卷号: 14, 页码: 23
作者:
Guo, Mingwei
;
Shen, Fei
;
Guo, Xiaozhen
;
Zhang, Jun
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Spectral Hardening Reveals Afterglow Emergence in Long-duration Fast X-Ray Transients: A Case Study of GRB 250404A/EP250404a
期刊论文
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ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 989, 期号: 2, 页码: L39
作者:
Yin, Yi-Han Iris
;
Fang, Yuan
;
Zhang, Bin-Bin
;
Deng, Chen
;
Yang, Jun
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A polysaccharide from
Gynostemma
pentaphyllum:
structure characterization and anti-insulin resistance potential through Galectin-3 modulation
期刊论文
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 310, 页码: 8
作者:
Ren, Mingwang
;
Sun, Guoqing
;
Ding, Xiaoyu
;
Yu, Xiaolin
;
He, Li
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Analysis of ligustrazine covalent cyclodextrin frameworks in bioinformatics and network pharmacology-based acute lung injury treatment
期刊论文
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ARABIAN JOURNAL OF CHEMISTRY, 2025, 卷号: 18, 期号: 4, 页码: 12
作者:
Wu, Di
;
Wang, Xiao Le
;
Jia, Yu
;
He, Si Yu
;
Gao, Ya Ting
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Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
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ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
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GRB 240529A: A Tale of Two Shocks
期刊论文
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ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 976, 期号: 2
作者:
Sun, Tian-Rui
;
Geng, Jin-Jun
;
Yan, Jing-Zhi
;
Hu, You-Dong
;
Wu, Xue-Feng
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