中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
合肥物质科学研究院 [3]
烟台海岸带研究所 [2]
计算技术研究所 [1]
化学研究所 [1]
光电技术研究所 [1]
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OAI收割 [17]
内容类型
期刊论文 [15]
会议论文 [2]
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2025 [4]
2024 [3]
2023 [3]
2018 [1]
2017 [1]
2015 [2]
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学科主题
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Design, synthesis, and biological activity of novel
para
-substituted phenylamino and phenyl derivatives of northebaine as selective delta opioid receptor agonists
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 130, 页码: 13
作者:
Zhang, Denggao
;
Gui, Jiangwen
;
Kong, Linghui
;
Hu, Chuyuan
;
Kou, Xinmeng
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/12/04
4,5-Epoxymorphinans
DOR-selective agonists
Structure-activity relationships
Structure-Activity Relationship of
N
-Cyclopropylmethyl-7α-[
para
-(arylcarboxamido)phenyl]-6,14-
endo
ethano-tetrahydronorthebaines as Potent and Selective Kappa Opioid Receptor Agonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 15, 页码: 15889-15909
作者:
Kong, Linghui
;
Yao, Songyu
;
Zhang, Denggao
;
Gui, Jiangwen
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/12/04
Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 15
作者:
Tang, Siyuan
;
Hu, Shuyang
;
Feng, Lijing
;
Kong, Linghui
;
Gui, Jiangwen
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2025/05/27
N-Cyclopropylmethyl-nornepenthones
Structure-activity relationship
MOR antagonist
KOR agonist
Substance use disorder
O
-Cyanobenzaldehydes Irreversibly Modify Both Buried and Exposed Lysine Residues in Live Cells
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 14, 页码: 11955-11963
作者:
Ling, Huan
;
Li, Lin
;
Duan, Liping
;
Huang, Weixue
;
Zheng, Jiangnan
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2025/05/27
iMeta
Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health
期刊论文
OAI收割
IMETA, 2024, 卷号: 3, 期号: 6, 页码: 19
作者:
Wang, Yao
;
Hou, Huiyu
;
Luo, Hao
;
Xun, Jiani
;
Ma, Chuang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/07/21
Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting
β
-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 36
作者:
Zhu, Wenhua
;
Liu, Cuiting
;
Xi, Kang
;
Li, Anqi
;
Shen, Li-an
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2024/08/20
Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1079-1092
作者:
Qin, Shaozhao
;
Feng, Lijian
;
Zhao, Qingyi
;
Yan, Ziqin
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2024/02/27
Mechanical response and data-driven fatigue model of interlayer soils in track-bed considering multi-factor coupling effect
期刊论文
OAI收割
COMPUTERS AND GEOTECHNICS, 2023, 卷号: 163, 页码: 18
作者:
Duan, Shuqian
;
Zhang, Minghuan
;
Xu, Dingping
;
Xiong, Jiecheng
;
Cui, Yujun
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/06/27
Interlayer soils
Cyclic triaxial tests
Fatigue model
Data-driven approach
Permanent strain
Norgestrel causes digestive gland injury in the clam Mactra veneriformis: An integrated histological, transcriptomics, and metabolomics study
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 871, 页码: 13
作者:
Zhao, Xiaoran
;
Wang, Qing
;
Li, Xiangfei
;
Xu, Hua
;
Ren, Chuanbo
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/11/08
Progestin
Histology
Transcriptome
Metabolome
Bivalve
Norgestrel causes digestive gland injury in the clam Mactra veneriformis: An integrated histological, transcriptomics, and metabolomics study
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 871, 页码: 13
作者:
Zhao, Xiaoran
;
Wang, Qing
;
Li, Xiangfei
;
Xu, Hua
;
Ren, Chuanbo
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2023/11/15
Progestin
Histology
Transcriptome
Metabolome
Bivalve