中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [5]
上海药物研究所 [3]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2024 [1]
2023 [1]
2021 [1]
2017 [1]
2016 [4]
学科主题
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A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 107, 页码: 19
作者:
Wang, Xiaoyan
;
Yun, Ying
;
Chen, Lili
;
Guo, Shimeng
;
Niu, Buying
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/07/12
Diabetes
GLP-1 receptor
Agonist
Structural optimization
Water molecule replacement
Structure activity relationship
Docking simulation
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12
作者:
Song, Zhaoxiang
;
Lu, Dan
;
Sun, Jun
;
Ye, Yangliang
;
Fang, Jiahui
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2024/01/16
GPR35
IBD
Lodoxamide
GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 2, 页码: 941-957
作者:
Wang, Congcong
;
Zhang, Yu-Fang
;
Guo, Shimeng
;
Zhao, Quan
;
Zeng, Yanping
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
Clinical application of a microfluidic chip for immunocapture and quantification of circulating exosomes to assist breast cancer diagnosis and molecular classification
期刊论文
OAI收割
PLOS ONE, 2017, 卷号: 12
作者:
Fang, Shimeng
;
Tian, Hongzhu
;
Li, Xiancheng
;
Jin, Dong
;
Li, Xiaojie
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2017/10/29
A novel microfluidic model can mimic organ-specific metastasis of circulating tumor cells
期刊论文
OAI收割
ONCOTARGET, 2016, 卷号: 7, 期号: 48, 页码: 78421-78432
作者:
Liu, Tingjiao
;
Kong, Jing
;
Luo, Yong
;
Jin, Dong
;
An, Fan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2017/10/29
microfluidic
metastasis
circulating tumor cells
multi-organ
bionic model
Carcinoma-Associated Fibroblasts Lead the Invasion of Salivary Gland Adenoid Cystic Carcinoma Cells by Creating an Invasive Track
期刊论文
OAI收割
PLOS ONE, 2016, 卷号: 11, 期号: 3
作者:
Li, Jiao
;
Jia, Zhuqiang
;
Kong, Jing
;
Zhang, Fuyin
;
Fang, Shimeng
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/06/20
Biomimetic tumor-induced angiogenesis and anti-angiogenic therapy in a microfluidic model
期刊论文
OAI收割
RSC ADVANCES, 2016, 卷号: 6, 期号: 42, 页码: 35248-35256
作者:
Liu, Lilu
;
Xie, Zhaorong
;
Zhang, Wenyuan
;
Fang, Shimeng
;
Kong, Jing
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/06/20
Application of a microfluidic-based perivascular tumor model for testing drug sensitivity in head and neck cancers and toxicity in endothelium
期刊论文
OAI收割
RSC ADVANCES, 2016, 卷号: 6, 期号: 35, 页码: 29598-29607
作者:
Jin, Dong
;
Ma, Xiaochi
;
Luo, Yong
;
Fang, Shimeng
;
Xie, Zhaorong
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/06/20