中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
地理科学与资源研究所 [1]
采集方式
OAI收割 [15]
内容类型
期刊论文 [15]
发表日期
2025 [1]
2024 [1]
2023 [1]
2022 [1]
2021 [2]
2020 [1]
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学科主题
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Discovery of multi-chitinase inhibitors cinnamyl thiazolidinone compounds as candidates for insect growth regulators via ligand-based optimization strategies
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 306, 页码: 14
作者:
Jiang, Zhiyang
;
Shi, Dongmei
;
Fu, Haoyu
;
Li, Yan
;
Zou, Renxuan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/05/27
Multi-chitinase inhibitor
Cinnamaldehyde compounds
Thiazolidinone compounds
Ligand-based optimization
Insect growth regulators (IGRs)
Flowering in the Northern Hemisphere is delayed by frost after leaf-out
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 11
作者:
Qiu, Haoyu
;
Yan, Qin
;
Yang, Yuchuan
;
Huang, Xu
;
Wang, Jinmei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/12/30
Combined inhibition of PARP and ATR synergistically potentiates the antitumor activity of HER2-targeting antibody-drug conjugate in HER2-positive cancers
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2023, 卷号: 13, 期号: 1, 页码: 161-+
作者:
Li, Yongpeng
;
Li, Lin
;
Fu, Haoyu
;
Yao, Qing
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/10/17
Antibody-drug conjugate
DS-8201
PARP
ATR
synergy
DNA damage
Trastuzumab in combination with PEGylated interferon-alpha 1b exerts synergistic antitumor activity through enhanced inhibition of HER2 downstream signaling and antibody-dependent cellular cytotoxicity
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2022, 卷号: 12, 期号: 2, 页码: 549-561
作者:
Xu, Piaopiao
;
Chen, Xiangling
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
  |  
收藏
  |  
浏览/下载:208/0
  |  
提交时间:2022/06/15
Trastuzumab
PEGylated IFN-alpha 1b
ADCC
HER2-positive cancer
synergistic effect
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
OAI收割
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
TSL-1502, a glucuronide prodrug of a poly (ADP-ribose) polymerase (PARP) inhibitor, exhibits potent anti-tumor activity in preclinical models
期刊论文
OAI收割
AMERICAN JOURNAL OF CANCER RESEARCH, 2021, 卷号: 11, 期号: 4, 页码: 1632-1645
作者:
Wang, Lei
;
Zhu, Xi
;
Li, Lili
;
Li, Lin
;
Fu, Li
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/06/11
PARP
DNA damage
hematologic toxicity
beta-glucuronidase
tumor selectivity
YES1amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer
期刊论文
OAI收割
BRITISH JOURNAL OF CANCER, 2020, 页码: 12
作者:
Wang, Lei
;
Wang, Quanren
;
Xu, Piaopiao
;
Fu, Li
;
Li, Yun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met
期刊论文
OAI收割
CANCER SCIENCE, 2019, 页码: 11
作者:
Tong, Mengya
;
Gao, Mingzhao
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2020/07/01
AZD9291
c-Met ADC
c-Met overexpression
resistance
SHR-A1403
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants
期刊论文
OAI收割
CANCER SCIENCE, 2019, 页码: 9
作者:
Gao, Mingzhao
;
Zhu, Hongmei
;
Fu, Li
;
Li, Yun
;
Bao, Xubin
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
AG-221
IDH2
leukemia
R140Q
R172K
Preclinical characterization of SHR6390, a novel CDK 4/6 inhibitor, invitro and in human tumor xenograft models
期刊论文
OAI收割
CANCER SCIENCE, 2019, 卷号: 110, 期号: 4, 页码: 1420-1430
作者:
Long, Fei
;
He, Ye
;
Fu, Haoyu
;
Li, Yun
;
Bao, Xubin
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/07/01
breast cancer
CDK 4/6
drug resistance
palbociclib
SHR6390