机构

• 上海药物研究所 [18]

采集方式

• OAI收割 [18]

内容类型

• 期刊论文 [17]
• 会议论文 [1]

发表日期

• 2024 [1]
• 2023 [2]
• 2022 [2]
• 2021 [2]
• 2020 [4]
• 2019 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共18条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CLpro Inhibitors as anti-SARS-CoV-2 Drug Candidate 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783 作者:  Jiang, Zhidong;  Feng, Bo;  Chen, Lu;  Nie, Tianqing;  Chen, Shizhao   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/09/26 Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18 作者:  Ren, Pengxuan;  Li, Hui;  Nie, Tianqing;  Jian, Xiaoqin;  Yu, Changyue   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/10/17 Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2 期刊论文  OAI收割 European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129 作者:  Ren, Pengxuan;  Yu, Changyue;  Zhang, Ruxue;  Nie, Tianqing;  Hu, Qiaoyu   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/03/26 In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2022, 卷号: 208, 页码: 10 作者:  Shang, Weijuan;  Dai, Wenhao;  Yao, Cheng;  Xu, Ling;  Tao, Xiangming   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/04/10 SARS-CoV-2  SARS-CoV-2 variants  FB2001  Main protease  PBPK  Anti-SARS-CoV-2 in vivo   Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 4, 页码: 2794-2808 作者:  Dai, Wenhao;  Jochmans, Dirk;  Xie, Hang;  Yang, Hang;  Li, Jian   |  收藏  |  浏览/下载：42/0  |  提交时间：2022/08/16 Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855 作者:  Zhou, Yu;  Fu, Yan;  Yin, Wanchao;  Li, Jian;  Wang, Wei   |  收藏  |  浏览/下载：29/0  |  提交时间：2021/05/24 Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20 作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia   |  收藏  |  浏览/下载：44/0  |  提交时间：2021/05/24 PDE4 inhibitors  Tetrahydroisoquinoline  Antipsoriasis   DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15 作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen   |  收藏  |  浏览/下载：64/0  |  提交时间：2020/12/24 DC591017  PDE4  Inflammation  Macrophages  Dendritic cells  Psoriasis   DC591017, a phosphodiesterase-4 (PDE4) inhibitor with robust anti-inflammation through regulating PKA-CREB signaling 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15 作者:  Li, Heng;  Li, Jian;  Zhang, Xianglei;  Feng, Chunlan;  Fan, Chen   |  收藏  |  浏览/下载：36/0  |  提交时间：2020/12/24 DC591017  PDE4  Inflammation  Macrophages  Dendritic cells  Psoriasis   Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease 期刊论文  OAI收割 SCIENCE, 2020, 卷号: 368, 期号: 6497, 页码: 1331-+ 作者:  Dai, Wenhao;  Zhang, Bing;  Jiang, Xia-Ming;  Su, Haixia;  Li, Jian   |  收藏  |  浏览/下载：49/0  |  提交时间：2020/12/24